Results 31 to 40 of about 3,494,904 (309)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The pinewood nematode (PWN) Bursaphelenchus xylophilus is a forestry quarantine pest and causes an extremely dangerous forest disease that is spreading worldwide.
Yibo An +9 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
. Influence of technogenic exhausts and nuclear pollution on the coniferous forests of Belarus
The large-scale environment pollution and its fatal influence on forest ecosystems has led to deterioration of a sanitary condition of forests in Belarus, to reduction of their biological resistance, to mass reproduction of many destructive insects and ...
S A Lamotkin +7 more
doaj
First mitogenome of Anthomyia illocata (Diptera, Anthomyiidae) yielded by next-generation sequencing
The mitochondrial genome of Anthomyia illocata Walker, 1857 belonging to the Anthomyiidae, was obtained using a next-generation sequencing approach. This 16,236 bp complete mitogenome consists of 13 protein-coding, two ribosomal RNA, and 22 transfer RNA ...
Henan Li +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Using the method of 1Н and 13С NMR spectroscopy, composition of balms of oleoresin of Pinus silvestris L, growing in different regions of the republic of Belarus, was studied.
E D Skakovskii +8 more
doaj
A recently presented taxonomical arrangement of the moss genus Orthotrichum Hedw. s.l. substantially changed the traditional view of the taxon that had been accepted throughout the twentieth century. This paper provides the results of mitogenomic studies
Jakub Sawicki +6 more
doaj +1 more source
Protection of valuable areas of local cultural heritage in sustainable development. Cultural parks in the Lodz Region [PDF]
Cultural park is one of the forms, in which valuable areas and historical establishments are protected under the Polish law. Protection covers “space” in its entirety with elements of wild nature and man-made structures.
Boryczka, Ewa +2 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

