Results 81 to 90 of about 3,494,904 (309)

The Attorney-Client Privilege Protection Act: The Prospect of Congressional Intervention into the Department of Justice\u27s Corporate Charging Policy [PDF]

open access: yes, 2008
This Note analyzes the Privilege Protection Act, focusing on how it might change corporate white-collar prosecutions. Part I of this Note explores the mechanics of the corporate privilege, the development of the DOJ\u27s waiver policy, and the structure
Gilman, Andrew
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Wings of war: how open-source intelligence reveals the impact of warfare in Ukraine amid global avian biodiversity decline

open access: yesThe European Zoological Journal
In this era of massive biodiversity loss, birds hold the dubious distinction of being at the forefront. Currently, 21% of avian species are vulnerable to extinction, and 6.5% are functionally extinct.
Ewa Węgrzyn   +5 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

HISTORICAL CHANGES IN THE AREA UNDER FOREST—ESTIMATION APPROACH BASED ON CARTOGRAPHIC RESOURCES

open access: yesZbornik Radova: Geografski institut "Jovan Cvijić"
This paper analyzes changes in forested areas, as depicted in topographic maps, within the historical context of their publication in Serbia. The research focuses on the experimental field “Goč-Gvozdac” of the University of Belgrade – Faculty of ...
Aleksandar Popović   +2 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Protecting Wildlife and Significant Habitat in Coastal New Hampshire [PDF]

open access: yes, 2003
The Great Bay Resource Protection Partnership (“Partnership”) consists of organizations and agencies that are committed to protecting the important habitats of the Great Bay area.
Nature Conservancy
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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