Results 181 to 190 of about 888,335 (393)

Efficacy of metoclopramide and dexamethasone for postoperative nausea and vomiting: a double-blind clinical trial

, 2010
Masood Entezariasl, Manouchehr Khoshbaten, Khatereh Isazadehfar, Godrat Akhavanakbari   +3 more
openalex   +1 more source

Breaking Barriers: Characterization of the Intradermal Lipopolysaccharide Challenge as an In Vivo Model for Controlled Induction of Vascular Leakage in Healthy Volunteers

Clinical Pharmacology &Therapeutics, EarlyView.
Vascular leakage and its associated phenomena vasodilation and endothelial activation are pathophysiological features of various diseases. Multiple drug candidates targeting these phenomena are in development, necessitating translational models to demonstrate proof‐of‐pharmacology and proof‐of‐mechanism in early‐phase clinical trials.
Marella Cornelia Elizabeth van Ruissen, Menno van Diemen, Liza Botros, Ingrid Tomljanovic, Hind Achbo, Dimitra Eleftheriou, Paul Willem Schenk, Naomi Bertine Klarenbeek, Derek William Gilroy, Manon Aleida Adriana Jansen, Matthijs Moerland   +10 more
wiley   +1 more source

Medicinal Plants for Chemotherapy-Induced Nausea and Vomiting: A Systematic Review of Antiemetic, Chemosensitizing, and Immunomodulatory Mechanisms

Therapeutics and Clinical Risk Management
Xue Sun,1,2 Fangfang Nie,1,2 Jizhuo Sun,1,2 Jingdong Zhang,2 Yuanhe Wang2 1The First Clinical College, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning Province, People’s Republic of China; 2Medical Oncology Department of ...
Sun X, Nie F, Sun J, Zhang J, Wang Y
doaj  

Bispectral index-guide anesthesia may reduce postoperative nausea and vomiting [PDF]

, 2012
M. Croci, M. F. Panzeri, E.Z.P Lepera, S. Hudecova, S. Fracassi, Serena Greco   +5 more
openalex   +1 more source

Comparison of post-operative shivering, nausea and vomiting between pre-intubation and pre-extubation intravenous paracetamol in percutaneous nephrolithotripsy under general anaesthesia

, 2023
Shalaka Nellore, Ankesh Jhunjhunwala, Mrunalini Kasod, Geeta Patkar   +3 more
openalex   +2 more sources

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia, Bhavya Gandhi, Faisal Quadri, Mahnoor Shahab, Kassie Rong, Genevieve Ramnarine, Ishleen Sudan, Sophia Zhang, Michelle Yu, Sara Mojdehi, Lawrence Mbuagbaw, Anne M. Holbrook   +11 more
wiley   +1 more source

Nausea and vomiting

Plastic and Reconstructive Surgery, 1984
openaire   +2 more sources

Flurbiprofen in patient-controlled intravenous analgesia and the risk of postoperative nausea and vomiting after gynecologic laparoscopy: a retrospective case-control study [PDF]

Jingru Chen, Qi Liu, Jingyuan Chen, Manting Xie, Yaping Rao, Peng Wang, Huang Wen-qi, Qiulan He   +7 more
openalex   +1 more source

Effect of Story-Telling on Reducing the Intensity of Nausea and Vomiting among Children Undergoing Chemotherapy [PDF]

, 2019
Semha El Sayed, Hekmat Ibrahim, Nahed Mohamed, Manal Ahmed   +3 more
openalex   +1 more source

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

Clinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen, Deena L. Hadi, Daniel A. Todd, Preston K. Manwill, John R. White, Matthew E. Layton, Nadja B. Cech, Kenneth E. Thummel, Mary F. Paine   +8 more
wiley   +1 more source