Results 51 to 60 of about 104,279 (240)
Advanced Science, EarlyView.This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin +18 more
wiley +1 more source
A Plug‐and‐Play Volume Minimizing Micromixer
Advanced Science, EarlyView.ABSTRACT Microscale fluid mixing has numerous applications where rapid and efficient mixing is required, including drug discovery, bio‐analysis and point‐of‐care diagnostics. Conventional soft lithography processes, however, make the integration of robust and reliable mixing difficult to implement in practice, especially across different flow rates ...
Kirill Kolesnik +3 more
wiley +1 more source
Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis
Advanced Science, EarlyView.Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim +16 more
wiley +1 more source
A corrida pela tecnologia para controlar o Prata, na rota de Riachuelo [PDF]
Navigator, 2015 The Naval Battle of Riachuelo, a combat that helped to change the course of the Paraguayan War in the initial phase of the conflict, can be analyzed from the point of view of the race for naval technology.
Fernando Ribas De Martini
doaj
THE PROBLEMS OF WORK OF THE MILITARY SEA COUNCIL IN THE YEARS OF THE BOARD OF KARL I STUART
Гуманитарные и юридические исследования, 2021 The Naval Council, which was created in the years of Henry VIII, became the body that effectively provided the permanent work of the English navy. The Navy that turned into the state institute in the Tudor epoch successfully solved the tasks of defense ...
S. Gavrilov
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EXPERIENCE OF THE INPUT-OUTPUT MODELS APPLICATION TO THE MOLDOVAN ECONOMY
Economy and Sociology, 2019 The main goal of this article is to present an overview of the input-output models which have been applied to Moldovan economy development study. We examined: static input-output model, dynamic input output model restricted by limited energy resources ...
Elvira NAVAL
doaj +1 more source
Advanced Science, EarlyView.This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu +7 more
wiley +1 more source
Machine Learning for Green Solvents: Assessment, Selection and Substitution
Advanced Science, EarlyView.Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta +4 more
wiley +1 more source
A Review on Navigating Sustainable Naval Design: LCA and Innovations in Energy and Fuel Choices
Journal of Marine Science and EngineeringThe naval sector holds paramount importance for the global economy, yet it entails significant environmental impacts throughout the entire life cycle of ships.
Filippo Cucinotta +2 more
doaj +1 more source
Identidad personal, hábito y educación
Tópicos, 2013 Some contemporary approaches to the problem of personal identity have mislead the role of habits and education in the constitution of this identity. For a proper conception of the developing of the self, one must understand the interaction among habits ...
Concepción Naval
doaj +1 more source