Results 111 to 120 of about 168,685 (307)

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

The Efficacy of Chaihu-Guizhi-Ganjiang Decoction on Chronic Non-Atrophic Gastritis with Gallbladder Heat and Spleen Cold Syndrome and Its Metabolomic Analysis: An Observational Controlled Before-After Clinical Trial

Drug Design, Development and Therapy
Tao Wen,1,* Xuan Liu,2,* Tao Pang,1,* Mingming Li,1 Guangyang Jiao,3 Xiangcheng Fan,1 Jigui Tang,4 Ci’an Zhang,4 Zhipeng Wang,1 Xiaoqiang Yue,4,* Wansheng Chen,1,3,5 Feng Zhang1,5 1Department of Pharmacy, Changzheng Hospital, Naval ...
Wen T, Liu X, Pang T, Li M, Jiao G, Fan X, Tang J, Zhang C, Wang Z, Yue X, Chen W, Zhang F   +11 more
doaj  

Mesoporous Silica Nanoparticles With Customized Drug Ratio/Loading for Effective Treatment of Gemcitabine‐Resistant Pancreatic Tumors

Advanced NanoBiomed Research, EarlyView.
Redox responsive mesoporous silica nanoparticles (MSNs) were engineered to deliver gemcitabine (Gem) and cisplatin (cisPt) at defined ratios to overcome chemoresistance in pancreatic ductal adenocarcinoma (PDAC). Optimized Gem MSNs and Gem cisPt MSNs enhanced cytotoxicity in murine and human Gem resistant models, with select formulations inducing ...
Tamanna Binte Huq, Sudip Kumar Dam, Doaha Awad, Punnya Anil Kumar Jeeja, Farzana Ferdous, Juan L. Vivero‐Escoto   +5 more
wiley   +1 more source

Two‐Dimensional Flow and Thermal Energy Transfer in Non‐Newtonian Casson–Carreau Ternary Hybrid Nanofluids Over Stationary and Moving Wedge Surfaces With Radiation and Magnetic Field Effects

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Efficient thermal management in advanced industrial systems requires improved heat transfer performance, particularly under non‐Newtonian fluid behavior and complex surface geometries. This study investigates the two‐dimensional flow and heat transfer characteristics of ternary hybrid nanofluids over both stationary and moving wedge surfaces ...
A. O. Akindele, A. M. Obalalu, M. O. Afolabi, Umair Khan, Samia Elattar   +4 more
wiley   +1 more source

Diprovocim protects against the radiation-induced damage via the TLR2 signaling pathway

Molecular Medicine
Severe ionizing radiation (IR) causes the acute lethal damage of hematopoietic system and gastrointestinal tract. By establishing a radiation injury model, we found that Diprovocim, a TLR2 agonist, protected mice against the lethal damage of ...
Duo Fang, Hainan Zhao, Lu Pei, Kai Jiang, Yuhan Gan, Xuanlu Zhai, Liao Zhang, Ying Cheng, Cong Liu, Jicong Du, Fu Gao   +10 more
doaj   +1 more source

Imaging and Linking Spatial Magnetic Nanoparticle Distribution to Microbead Torques Using Soft X‐Ray Laminography

Advanced Physics Research, EarlyView.
Nanoscale 3D imaging of superparamagnetic microbeads via soft X‐ray laminography reveals the structural origin of the observed torques in cell movement experiments. These microbeads are found to have an uneven distribution of magnetic magnetite nanoparticles.
Findan Block, Finn Klingbeil, Dennis Seidler, Christine Arndt, Sandra Sindt, Katharina Witte, Benjamin Watts, Jörg Raabe, Christine Selhuber‐Unkel, Jeffrey McCord   +9 more
wiley   +1 more source

Intranasal S-2P and lentinan formulation confers broad protection against SARS-CoV-2 VOCs via IFN-γ-dominant mechanisms

npj Vaccines
Effective respiratory mucosal vaccines remain urgently needed to mitigate the rapid mutation and transmission of SARS-CoV-2. Here, we demonstrated that the spike protein (S-2P) of ancestral SARS-CoV-2 acted as a self-adjuvanted antigen for intranasal ...
Zhendong Pan, Xu Zheng, Liangliang Jiang, Cuiling Ding, Yangang Liu, Haoran Peng, Yan Liu, Yanhua He, Wanda Tang, Congcong Zhang, Dawei Wang, Xiaoyan Zhang, Jianqing Xu, Zhongtian Qi, Wen Wang, Ping Zhao   +15 more
doaj   +1 more source

Arthroscopic Posterior Labral Repair in Professional Contact Athletes Restores Shoulder Stability and Enables Successful Return to Pre‐injury Competition

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate return‐to‐competition rates, posterior shoulder instability recurrences, and revision surgeries following arthroscopic posterior labral repair in this elite cohort. Methods A retrospective review of prospectively collected data included professional contact athletes undergoing primary arthroscopic posterior labral repair by a single
Ayham Jaber, Lorenz Fritsch, Michael Nocek, Christopher J. Hawryluk, Maximilian Hinz, Matthew T. Provencher, Peter J. Millett   +6 more
wiley   +1 more source

Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance

Molecular Cancer, 2021
Lei Liu, Yuanyuan Chen, Yijuan Huang, Kun Cao, Tingting Liu, Hui Shen, Jianguo Cui, Bailong Li, Jianming Cai, Fu Gao, Yanyong Yang   +10 more
doaj   +1 more source

Integrating yoga into anatomy and clinical medicine education: A holistic approach to learning

Anatomical Sciences Education, EarlyView.
Abstract Anatomical knowledge is fundamental for success in clinical settings. Unfortunately, anatomy education within professional health programs has experienced a continual decrease in contact hours and curricular content over the previous two decades, leading to deficits and potential gaps in anatomical science knowledge.
Dana Rohde, Madeleine E. Norris, Jennifer R. Kinder, Barbie Klein, Derek Harmon   +4 more
wiley   +1 more source