Results 31 to 40 of about 403,915 (345)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Self-supervised machine learning for live cell imagery segmentation
Communications Biology, 2022 A self-supervised learning approach uses cellular motion between consecutive images to self-train a machine learning classifier for cell segmentation.
Michael C. Robitaille +3 more
doaj +1 more source
A Neural Model of How the Cortical Subplate Coordinates the Laminar Development of Orientation and Ocular Dominance Maps [PDF]
, 2002 Air Force Office of Scientific Research (F49620-98-1-0108, F49620-0 1-1-0397); Defense Advanced Research Projects Agency and the Office of Naval Research (N00014-95-1-0409); National Science Foundation (IIS-97-20333); Office of Naval Research (N00014-01 ...
Grossberg, Stephen, Seitz, Aaron
core +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Amur River Flotilla base near Khabarovsk as an example of far eastern military urbanism. 1908-1918
АрхитектонThe article, written on the basis of material found in the archives of Moscow, St. Petersburg and Vladivostok, presents the results of the first year of the research project “Military Theme in the Architectural and Spatial Development of the Far East ...
Ivanova Alina P. +2 more
doaj +1 more source
A Successful First Pattullo Conference [PDF]
Oceanography, 2009 Initiated in 2004, MPOWIR (Mentoring Physical Oceanography Women to Increase Retention) is a community-initiated and community-led program aimed at providing mentoring to junior women in physical oceanography in order to improve their retention in the ...
M. Susan Lozier
doaj
Linking Visual Cortical Development to Visual Perception [PDF]
, 2000 Defense Advanced Research Projects Agency and the Office of Naval Research (N00014-95-1-0409); National Science Foundation (IRI-97-20333); Office of Naval Research (N00014-95-1 ...
Grossberg, Stephen
core +1 more source
Data‐Driven Distributed Safe Control Design for Multi‐Agent Systems
International Journal of Adaptive Control and Signal Processing, EarlyView.This paper presents a data‐driven control barrier function (CBF) technique for ensuring safe control of multi‐agent systems (MASs) with uncertain linear dynamics. A data‐driven quadratic programming (QP) optimization is first developed for CBF‐based safe control of single‐agent systems using a nonlinear controller. This approach is then extended to the
Marjan Khaledi, Bahare Kiumarsi
wiley +1 more source
Russian Naval Artillery Exercise in the 18th Century: Functioning, Borrowings, and Innovations
Historia provinciae: журнал региональной историиThe article is devoted to the issue of the development of Russian naval artillery exercise in the 18th century. The author discovered previously unknown lists of command sequences with their descriptions related to the Russian naval artillery exercise ...
Kirill B. Nazarenko
doaj +1 more source
Computation of pressures on under-water-bodies [PDF]
, 1987 An existing code in the division is utilized to obtain pressures on under-water-bodies supplied by the User agency (Naval Science and Technology, Vishakapatnam ...
Ramamoorthy, P, Sarasamma, VR
core