Results 61 to 70 of about 62,394 (260)

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Metallurgical Investigation of HSLA Steel Subjected to Underwater Explosion

Shock and Vibration, 1994
The metallurgical behaviour of HSLA steel subjected to underwater explosion is of prime importance because of its structural applications in underwater vehicles.
V. Bhujanga Rao, R. Rajendran, A.V. Jaykumar, K.H.B.S. Satyanarayana   +3 more
doaj   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Serum amino acid alterations in hyperuricemia: potential targets for renal disease prevention

Amino Acids
Observational studies have linked uric acid (UA) levels and kidney disease to amino acid homeostasis, but the causal relationship is unclear. This study aims to determine if elevated UA affects amino acid levels and whether amino acids mediate this ...
Qinglin Sheng, Yuqing Ma, Bingjie Geng, Jiahui Chen, Junfei Cheng, Su Liu, Rui Li, Xiangtong Li, Jing Wang, Hongtao Lu, Fangyuan Gao, Fu Gao   +11 more
doaj   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

A Promising Application of Injectable Hydrogels in Nerve Repair and Regeneration for Ischemic Stroke

International Journal of Nanomedicine
Yuan Gao,1,2,* Ting-Lin Zhang,3,* Hong-Jian Zhang,1,2,* Jie Gao,3 Peng-Fei Yang1,2,4 1Oriental Pan-Vascular Devices Innovation College, University of Shanghai for Science and Technology, Shanghai, People’s Republic of China; 2School of Health
Gao Y, Zhang TL, Zhang HJ, Gao J, Yang PF   +4 more
doaj  

Reinnervation of Muscle Targets Enhances the Separability of Motor Unit Signals Following Peripheral Nerve Transfers

Advanced Science, EarlyView.
Injured or cut peripheral nerves can be surgically rerouted to reinnervate new muscle targets. This study demonstrates reinnervated muscles exhibit enhanced separability between individual motor unit signals, which can simplify signal recording and decomposition. These findings highlight the potential of reinnervated muscle to serve as a key biological
Kiara N Quinn, Siyu Wang, Lang Qin, Alessandro Ascani Orsini, Kenzi Griffith, Rachana Suresh, Fausto Kang, Pierce L Perkins, Neha Joshi, Alexis L Lowe, Sami Tuffaha, Nitish V Thakor   +11 more
wiley   +1 more source

Comparative Effectiveness of Pharmacological, Non-Pharmacological, and Combined Strategies for Pain Relief During Colonoscopy: A Bayesian Network Meta-Analysis of Randomized Trials

Journal of Pain Research
Xiaonan Huang,1,* Shan Tian,2,* Lifan Xu,1,* Juhan Chen,1,* Hao Wang,3 Tingting Mai,1 Lei Shi,1 Han Wang,4 Mengcheng Cai,5 Fanfu Fang1 1Department of Rehabilitation Medicine, Changhai Hospital, Naval Medical University ...
Huang X, Tian S, Xu L, Chen J, Wang H, Mai T, Shi L, Wang H, Cai M, Fang F   +9 more
doaj  

Fault diagnosis for pump equipment based on transfer learning: the domain generalization method

Scientific Reports
In recent years, with the advent of machine learning technology, data-driven fault diagnosis has emerged as a prominent research area. However, since the necessity of training and test data has to follow an identical distribution, the conventional data ...
Weihong Wang, Xinwen Zhao, Yongfa Zhang, Tian Tan, Lizhi Jiang, Chen Wang, Liming Zhang   +6 more
doaj   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source