Results 101 to 110 of about 39,435 (236)

Multiple‐TE Based Blood–Brain‐Barrier Water Exchange Time Measurement Using a TE‐Resolved 3D TSE Stack‐Of‐Spirals Readout

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1629-1644, October 2026.
ABSTRACT Purpose To develop a slice‐wise blurring‐free and densely sampled TE‐resolved multiple‐TE (mTE) ASL sequence (TASL) for measuring blood–brain barrier (BBB) water exchange time. Methods A 3D TSE spiral‐readout pCASL sequence was modified to enable TE‐resolved acquisition.
Bo Li   +11 more
wiley   +1 more source

Quizartinib in Combination With FLAG‐IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG‐QUIDA): A PETHEMA Phase I‐II Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2258-2268, September 2026.
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal   +29 more
wiley   +1 more source

Patient‐Centric First‐in‐Human Dose Selection: An Ex Vivo Minimal Anticipated Biological Effect Level Approach for T‐Cell Engagers in Multiple Myeloma

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 745-752, September 2026.
The minimal anticipated biological effect level (MABEL) approach to first‐in‐human (FIH) dose calculation can lead to long dose‐escalation periods before observing clinical activity. We used a novel ex vivo MABEL approach to calculate the FIH starting dose for forimtamig, a T‐cell bispecific antibody under investigation for the treatment of relapsed ...
Thomas E. Kraft   +16 more
wiley   +1 more source

Decoding the Heterogeneity of Diffuse Large B‐Cell Lymphomas: A Comprehensive Genetic, Transcriptomic, and Phenotypic Profiling of B‐Cell Lymphoma Cell Lines

open access: yesHematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) is the most prevalent form of non‐Hodgkin lymphoma, exhibiting significant molecular and clinical heterogeneity. Advances in classification integrating phenotypic, genetic, and transcriptomic features have improved diagnosis and prognosis.
Marina Pérez‐Aguilera   +14 more
wiley   +1 more source

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1139-1152, 1 September 2026.
What's new? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille   +25 more
wiley   +1 more source

Meat Intake and Risk of Gastric and Esophageal Adenocarcinoma in the European Prospective Investigation Into Cancer and Nutrition (EPIC) Study

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1176-1187, 1 September 2026.
Limited evidence links processed meat intake and non‐cardia gastric cancer, while esophageal adenocarcinoma is increasing in Western countries, where diets are typically high in red and processed meats. Using data from over 450,000 participants from a large prospective study, the authors examined meat consumption and the risk of gastric and esophageal ...
Catalina Bonet   +25 more
wiley   +1 more source

The Zooplankton International Geospatial dataset: A global repository of spatiotemporal freshwater zooplankton community composition data from lakes and reservoirs to support ecological research

open access: yesLimnology and Oceanography Letters, Volume 11, Issue 5, September 2026.
Abstract Zooplankton transfer substantial energy in aquatic food webs and are used as indicators of environmental change. Syntheses of zooplankton community dynamics globally require datasets that span a wide range of environmental gradients; however, these datasets are limited due to methodological differences across programs, taxonomic ...
Stephanie E. Figary   +142 more
wiley   +1 more source

The Fertility Effects of Reducing Implicit Childcare Subsidies: The Case of School Schedules

open access: yesJournal of Policy Analysis and Management, Volume 45, Issue 4, Fall 2026.
ABSTRACT Despite governments’ efforts to raise fertility through family‐support policies, birth rates continue to decline in high‐ and middle‐income countries. Some policies designed for other purposes, however, may function as implicit childcare subsidies.
Álvaro Muñiz‐Fernández
wiley   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, Volume 36, Issue 5, September 2026.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

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