Results 241 to 250 of about 338,520 (307)

A Hybrid <i>θ</i>*-APF-Q Framework for Energy-Aware Path Planning of Unmanned Surface Vehicles Under Wind and Current. [PDF]

Sensors (Basel)
Sun X, Dong Z, Chen X, Sun L, An Y.
europepmc   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Enhanced pure pursuit with dynamic steering control for autonomous mobile robots and application to safe navigation in chemical plants. [PDF]

Sci Rep
Promkaew N, Junhuathon N, Phuphaphud A, Kulvanit P, Sukpancharoen S.   +4 more
europepmc   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

Advanced Science, EarlyView.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang, Wanhui Dong, Jian Chen, Zhangjie Zhou, Shujuan Fu, Tingting Wu, Haiyan Jiang, Zhiying Wang, Zhixian Zhong, Yi Zhong   +9 more
wiley   +1 more source

Early experience with a rapid navigation system-assisted unilateral biportal endoscopic interbody fusion for lumbar spondylolisthesis. [PDF]

Front Surg
Peng C, Ren Z, Wang J, Zhang J, Qin Y, Yu L, Zhu G, Hao Y.   +7 more
europepmc   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Nanorobotic Approaches Against Multidrug-Resistant Infections: Design, Principle, Mechanistic Innovation, Translational Challenges and Biomedical Applications. [PDF]

Molecules
Sayad U, Rahman SU, Khalil AAK, Ullah A, Ullah S, Büyüker SM.   +5 more
europepmc   +1 more source

Feasibility and Safety of a Robotic-Assisted Optical Navigation System for Pulmonary Nodule Percutaneous Cryoablation: A Prospective, Single-Center, Single-Arm Pilot Study.

Respiration
Wu X, Wan W, Yang L, Shi X, Lin J, Luo W, Wang X, Lu G, Chen Y, Li S.   +9 more
europepmc   +1 more source

An Augmented Reality-Based Navigation System for Stereotactic Brain Biopsy with Multi-Objective Path Planning and Hybrid Registration. [PDF]

Brain Sci
Zhang T, Wang S, Zhong Y, Li H, Hu J, Wang H.   +5 more
europepmc   +1 more source