Results 81 to 90 of about 23,684,708 (387)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Research on Remote GPS Common-View Precise Time Transfer Based on Different Ionosphere Disturbances

open access: yesSensors, 2020
Propagation path delays are a major error for the remote precise time transfer of common view; these path delays contain the ionosphere and troposphere impact, while the contributions of the ionosphere and the troposphere from common-view satellites to ...
Jingkui Zhang   +4 more
doaj   +1 more source

Autonomous navigation of the space debris collector [PDF]

open access: yesINCAS Bulletin, 2019
The article discusses potential use of proposed by the authors configuration of onboard system of autonomous navigation and movement control of space debris collector to operate at GSO.
Dmitriy A. KOZOREZ, Dmitriy M. KRUZHKOV
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

A Minimal Solution for Binocular Camera Relative Pose Estimation Based on the Gravity Prior

open access: yesRemote Sensing
High-precision positioning is the foundation for the functionality of various intelligent agents. In complex environments, such as urban canyons, relative pose estimation using cameras is a crucial step in high-precision positioning. To take advantage of
Dezhong Chen   +3 more
doaj   +1 more source

Impact Assessment of GNSS Spoofing Attacks on INS/GNSS Integrated Navigation System

open access: yesItalian National Conference on Sensors, 2018
In the face of emerging Global Navigation Satellite System (GNSS) spoofing attacks, there is a need to give a comprehensive analysis on how the inertial navigation system (INS)/GNSS integrated navigation system responds to different kinds of spoofing ...
Yang Liu, Sihai Li, Q. Fu, Zhenbo Liu
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Pedestrian Dead Reckoning Based on Motion Mode Recognition Using a Smartphone

open access: yesSensors, 2018
This paper presents a pedestrian dead reckoning (PDR) approach based on motion mode recognition using a smartphone. The motion mode consists of pedestrian movement state and phone pose.
Boyuan Wang   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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