Review: “The Disappointment Dilemma: Short‐ and Long‐Term Learning From Negative Outcomes”
The habenula routes negative‐outcome signals to VTA, RMTg, and IPN to shape aversive learning and motivation. The lateral habenula encodes acute negative prediction errors to rapidly adapt behavior to threat, fear, and avoidance. The medial habenula integrates repeated stress, drug, and aversive experiences into long‐term negative mood and expectations.
Ines Ibañez‐Tallon +4 more
wiley +1 more source
Characterizing inspiratory duty cycle compensation to flow-limited breathing during drug-induced sleep endoscopy in obstructive sleep apnea. [PDF]
Kane BL, Gouldman KP, Yu JL.
europepmc +1 more source
Alzheimer\u27s disease pathology and shunt surgery outcome in normal pressure hydrocephalus [PDF]
Batra, Sachin +11 more
core +1 more source
Structure‐ and Ligand‐Based Discovery of Novel 3‐Chymotrypsin‐Like Protease Nonpeptidomimetic Hits
A multistep virtual screening cascade, integrating shape‐based, ensemble docking, and quantitative structure–activity relationship (QSAR) models, was employed to screen 1.5 million compounds. This funnel identified a novel 3‐chymotrypsin‐like protease (3CLpro) inhibitor, LabMol‐499, which was experimentally validated using a Förster Resonance Energy ...
Sabrina Silva‐Mendonça +14 more
wiley +1 more source
Relative Risk of Neovascular Age-Related Macular Degeneration Following Cataract Surgery. [PDF]
Bellanda V +8 more
europepmc +1 more source
Applying the small vulnerable newborns classification in the US context. [PDF]
Chock EY +4 more
europepmc +1 more source
The Translational Science Benefits Model: A New Framework for Assessing the Health and Societal Benefits of Clinical and Translational Sciences [PDF]
American Academy of Pediatrics +35 more
core +2 more sources
Evidence-based team intervention to reduce diagnostic errors in anaemia and CKD diagnoses in primary care: protocol for a stepped-wedge cluster RCT. [PDF]
Novikov Z +15 more
europepmc +1 more source
Pathogenic CGG expansions in oculopharyngodistal myopathy exhibit distinct characteristics of each causative gene on the flanking sequences as well as methylation status. [PDF]
Eura N +9 more
europepmc +1 more source

