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The lingering effects of Neanderthal introgression on human complex traits
The genetic variants introduced into the ancestors of modern humans from interbreeding with Neanderthals have been suggested to contribute an unexpected extent to complex human traits.
Xinzhu Wei +9 more
doaj +3 more sources
Late Pleistocene Neanderthal exploitation of stable and mosaic ecosystems in northern Iberia shown by multi-isotope evidence [PDF]
During the last glacial period, rapidly changing environments posed substantial challenges to Neanderthal populations in Europe. Southern continental regions, such as Iberia, have been proposed as important climatic “buffer” zones during glacial phases ...
Sarah Pederzani +5 more
openalex +2 more sources
Neanderthal introgression in SCN9A impacts mechanical pain sensitivity
The Nav1.7 voltage-gated sodium channel plays a key role in nociception. Three functional variants in the SCN9A gene (encoding M932L, V991L, and D1908G in Nav1.7), have recently been identified as stemming from Neanderthal introgression and to associate ...
Pierre Faux +32 more
doaj +2 more sources
The Neanderthal niche space of Western Eurasia 145 ka to 30 ka ago
Neanderthals occupied Western Eurasia between 350 ka and 40 ka ago, during the climatically volatile Pleistocene. A key issue is to what extent Neanderthal populations expanded into areas of Western Eurasia and what conditions facilitated such range ...
Peter M. Yaworsky +2 more
doaj +2 more sources
Neanderthal teeth from
Objectives: We reassess the taxonomic assignment and stratigraphic context of a permanent upper first molar and a permanent lower third premolar recovered from the archeological site of Lezetxiki in the North of the Iberian Peninsula.
Diego López‐Onaindia +4 more
openalex +2 more sources
Neanderthal coexistence with Homo sapiens in Europe was affected by herbivore carrying capacity [PDF]
It has been proposed that climate change and the arrival of modern humans in Europe affected the disappearance of Neanderthals due to their impact on trophic resources; however, it has remained challenging to quantify the effect of these factors.
Marco Vidal‐Cordasco +3 more
openalex +2 more sources
There are many opinions and arguments about the types of weapons that Neanderthals may have used. We list five assumptions about Neanderthal weapon-assisted hunting and suggest that the tip cross-sectional area (TCSA) approach may be used to assess these,
Marlize Lombard, Marie-Hélène Moncel
doaj +2 more sources
Calculated or caring? : Neanderthal healthcare in social context [PDF]
Explanations for patterns of healed trauma in Neanderthals have been a matter of debate for several decades. Despite widespread evidence for recovery from injuries or survival despite impairments, apparent evidence for healthcare is given limited ...
Hitchens, Gail Elizabeth +3 more
core +3 more sources
Quantifying the contribution of Neanderthal introgression to the heritability of complex traits
We lack a comprehensive understanding of how Neanderthal ancestry influences human traits. This study finds that regions with Neanderthal ancestry are broadly depleted of trait-associated variation; yet, introgressed variants likely contributed to human ...
Evonne McArthur +2 more
doaj +2 more sources
Background Introgression from extinct Neanderthal and Denisovan human species has been shown to contribute to the genetic pool of modern human populations and their phenotypic spectrum.
Dora Koller +7 more
doaj +2 more sources

