Results 21 to 30 of about 23,501 (199)

Neanderthal introgression in SCN9A impacts mechanical pain sensitivity

open access: yesCommunications Biology, 2023
The Nav1.7 voltage-gated sodium channel plays a key role in nociception. Three functional variants in the SCN9A gene (encoding M932L, V991L, and D1908G in Nav1.7), have recently been identified as stemming from Neanderthal introgression and to associate ...
Pierre Faux   +32 more
doaj   +1 more source

Blood groups of Neandertals and Denisova decrypted.

open access: yesPLoS ONE, 2021
Blood group systems were the first phenotypic markers used in anthropology to decipher the origin of populations, their migratory movements, and their admixture.
Silvana Condemi   +6 more
doaj   +1 more source

Recent origin of low trabecular bone density in modern humans [PDF]

open access: yes, 2014
Humans are unique, compared with our closest living relatives (chimpanzees) and early fossil hominins, in having an enlarged body size and lower limb joint surfaces in combination with a relatively gracile skeleton (i.e., lower bone mass for our body ...
Bernhard Zipfel   +11 more
core   +1 more source

The Role of Chemistry Across Disciplines From Humanities to Life Sciences in Understanding Complexity and Emergence

open access: yesAngewandte Chemie, EarlyView.
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe   +5 more
wiley   +2 more sources

No ancient DNA damage in Actinobacteria from the Neanderthal bone. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: The Neanderthal genome was recently sequenced using DNA extracted from a 38,000-year-old fossil. At the start of the project, the fraction of mammalian and bacterial DNA in the sample was estimated to be
Katarzyna Zaremba-Niedźwiedzka   +1 more
doaj   +1 more source

Quantifying the contribution of Neanderthal introgression to the heritability of complex traits

open access: yesNature Communications, 2021
We lack a comprehensive understanding of how Neanderthal ancestry influences human traits. This study finds that regions with Neanderthal ancestry are broadly depleted of trait-associated variation; yet, introgressed variants likely contributed to human ...
Evonne McArthur   +2 more
doaj   +1 more source

The first Neanderthal remains from an open-air Middle Palaeolithic site in the Levant [PDF]

open access: yes, 2017
The late Middle Palaeolithic (MP) settlement patterns in the Levant included the repeated use of caves and open landscape sites. The fossil record shows that two types of hominins occupied the region during this period - Neandertals and Homo sapiens ...
Agha, Nuha   +21 more
core   +4 more sources

Evolution of the Human Brain: the key roles of DHA (omega-3 fatty acid) and Δ6-desaturase gene

open access: yesOilseeds and fats, crops and lipids, 2018
The process of hominization involves an increase in brain size. The development of hominids’ cognitive capital up to the emergence of Homo sapiens was due to interactive, iterative, and integrative coevolution, allowing positive selection.
Majou Didier
doaj   +1 more source

Neanderthal Hunting Weapons Re-Assessed: A Tip Cross-Sectional Area Analysis of Middle Palaeolithic Point Assemblages from South Eastern France

open access: yesQuaternary, 2023
There are many opinions and arguments about the types of weapons that Neanderthals may have used. We list five assumptions about Neanderthal weapon-assisted hunting and suggest that the tip cross-sectional area (TCSA) approach may be used to assess these,
Marlize Lombard, Marie-Hélène Moncel
doaj   +1 more source

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