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Evolutionary Origin of MUTYH Germline Pathogenic Variations in Modern Humans

open access: yesBiomolecules, 2023
MUTYH plays an essential role in preventing oxidation-caused DNA damage. Pathogenic germline variations in MUTYH damage its function, causing intestinal polyposis and colorectal cancer.
Fengxia Xiao   +6 more
doaj   +1 more source

On the Probability of Neanderthal Ancestry [PDF]

open access: yesThe American Journal of Human Genetics, 1998
I thank B. Bengtsson, A. Di Rienzo, P. Donnelly, R. Harding, the reviewers, and especially T. Nagylaki, for their comments on the manuscript. This work was supported by the Erik Philip-Sorensen Foundation.
openaire   +2 more sources

The Neanderthal Occupations at Veldwezelt-Hezerwater (Belgium) and the Challenge of the Eemian Forest in Northwest Europe

open access: yesPaleoAnthropology
The loess-paleosol sequences in the provinces of Belgian and Dutch Limburg (Northeastern Belgium and Southern Netherlands, respectively) reveal a continuous record of paleo-climatic variations during the late Middle and Upper Pleistocene.
Patrick Bringmans
doaj   +1 more source

Disease transmission and introgression can explain the long-lasting contact zone of modern humans and Neanderthals

open access: yesNature Communications, 2019
Modern humans and Neanderthals coexisted in the Levant for tens of thousands of years before modern humans spread and replaced Neanderthals. Here, Greenbaum et al. develop a model showing that transmission of disease and genes can explain the maintenance
Gili Greenbaum   +5 more
doaj   +1 more source

The Neanderthal niche space of Western Eurasia 145 ka to 30 ka ago

open access: yesScientific Reports
Neanderthals occupied Western Eurasia between 350 ka and 40 ka ago, during the climatically volatile Pleistocene. A key issue is to what extent Neanderthal populations expanded into areas of Western Eurasia and what conditions facilitated such range ...
Peter M. Yaworsky   +2 more
doaj   +1 more source

Anatomically modern human in the Châtelperronian hominin collection from the Grotte du Renne (Arcy-sur-Cure, Northeast France)

open access: yesScientific Reports, 2023
Around 42,000 years ago, anatomically modern humans appeared in Western Europe to the detriment of indigenous Neanderthal groups. It is during this period that new techno-cultural complexes appear, such as the Châtelperronian that extends from northern ...
Arthur Gicqueau   +10 more
doaj   +1 more source

Syphilis and Neanderthal Man [PDF]

open access: yesNature, 1971
BONE changes in Neanderthal remains which, it has been suggested1, might be caused by rickets are not unlike those seen in certain treponemal diseases, notably congenital syphilis. Examining the Neanderthal collection at the British Museum (Natural History), I noted several features compatible with treponemal disease.
openaire   +2 more sources

Landmark developments in the understanding of Neanderthal Disappearance

open access: yesGroundings, 2012
This essay deals with the evidence and theories surrounding the disappearance of Neanderthals from the archaeological record. The essay charts the development of our understanding of this event while assessing the media’s portrayal of archaeological ...
Lauren Davidson
doaj   +1 more source

Possible interbreeding in late Italian Neanderthals? New data from the Mezzena jaw (Monti Lessini, Verona, Italy).

open access: yesPLoS ONE, 2013
In this article we examine the mandible of Riparo Mezzena a Middle Paleolithic rockshelter in the Monti Lessini (NE Italy, Verona) found in 1957 in association with Charentian Mousterian lithic assemblages.
Silvana Condemi   +5 more
doaj   +1 more source

3D enamel profilometry reveals faster growth but similar stress severity in Neanderthal versus Homo sapiens teeth

open access: yesScientific Reports, 2021
Early life stress disrupts growth and creates horizontal grooves on the tooth surface in humans and other mammals, yet there is no consensus for their quantitative analysis.
Kate McGrath   +8 more
doaj   +1 more source

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