Results 141 to 150 of about 508,942 (290)

The Influence of Internal Structure on Physical Outcomes of the 2029 Apophis Close Approach with Earth

The Planetary Science Journal
The 2029 close approach between asteroid 99942 Apophis and Earth represents a unique opportunity to study the influence of tidal encounters on the deformation and rotational evolution of an S-complex near-Earth object in the 0.1–1 km size range—a class ...
Joseph V. DeMartini, Derek C. Richardson, Naomi Murdoch, Raphaël F. Garcia, Nicholas C. Schmerr, Petr Scheirich, Ronald-L. Ballouz, Adriana Daca   +7 more
doaj   +1 more source

Palomar Optical Spectrum of Hyperbolic Near-Earth Object A/2017 U1 [PDF]

, 2017
J. Masiero
openalex   +1 more source

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source

Candidate Main-belt Asteroids for Surface Heterogeneity

The Astronomical Journal
Large terrestrial bodies in our solar system like the Earth, Mars, Mercury, and the Moon exhibit geologically complex surfaces with compositional heterogeneity.
Sunao Hasegawa, Michaël Marsset, Francesca E. DeMeo, Josef Hanuš, Richard P. Binzel, Schelte J. Bus, Brian Burt, David Polishook, Cristina A. Thomas, Jooyeon Geem, Masateru Ishiguro, Daisuke Kuroda, Pierre Vernazza   +12 more
doaj   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

Divisions I & III WG: on Near Earth Objects [PDF]

, 2005
David Morrison, Andrea Milani, Richard P. Binzel, Ted Bowell, A. Carusi, C. R. Chapman, Alan W. Harris, Syuzo Isobe, B. G. Marsden, K. Muinonen, S. Ostro, Victor Shor, Duncan Steel, G. Tancredi, J. Tichá, G. B. Valsecchi, Don Yeomans   +16 more
openalex   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

THE MISSION ACCESSIBLE NEAR-EARTH OBJECTS SURVEY (MANOS): FIRST PHOTOMETRIC RESULTS [PDF]

, 2016
A. Thirouin, N. Moskovitz, R. P. Binzel, E. Christensen, F. E. DeMeo, M. J. Person, D. Polishook, C.A. Thomas, D. Trilling, M. Willman, M. Hinkle, Burt B, D. Avner, F. J. Aceituno, A. Thirouin, N. Moskovitz, R. P. Binzel, E. Christensen, F. E. DeMeo, M. J. Person, D. Polishook, C.A. Thomas, D. Trilling, M. Willman, M. Hinkle, Burt B, D. Avner, F. J. Aceituno   +27 more
openalex   +1 more source