Results 61 to 70 of about 171,503 (343)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Internal structure of Near-Earth Objects
Comptes Rendus. Physique, 2005 Abstract For the purposes of mitigation, the internal structure of near-Earth objects (NEOs) remains one of the most important but least understood parameters. From a science point of view, the internal structure is equally intriguing. Knowledge of the internal structure can reveal the collisional history, and in the case of comets, may also reveal ...
Binzel, Richard P., Kofman, Wlodek
openaire +3 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Investigating the Puzzling Synchrotron Behaviour of Mrk 421
Galaxies, 2016 We investigate the multiwavelength behaviour of the high-energy peaked BL Lac object (HBL) Mrk 421 at redshift z = 0 . 031 in the period 2007–2015.
Maria I. Carnerero +6 more
doaj +1 more source
WORKING GROUP: NEAR-EARTH OBJECTS [PDF]
Proceedings of the International Astronomical Union, 2011 Following its meeting in May, 2010, the IAU Executive Committee requested that a Working Group on NEOs within Div. III be re-activated and carry out the following activities: a) investigate and formulate requirements for an international ground- and/or space-based NEO survey, to detect, track and characterize (optical/IR, radar) 90% of all NEOs ...
David Morrison +2 more
openaire +2 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Asteroid Impact Hazard Warning from the Near-Earth Object Surveyor Mission
The Planetary Science JournalNASA’s Near-Earth Object Surveyor mission, scheduled for launch in 2027 September, is designed to detect and characterize at least two-thirds of the potentially hazardous asteroids with diameters larger than 140 m in a nominal 5 yr mission. We describe a
Oliver Lay +5 more
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source