Results 61 to 70 of about 508,942 (290)

Discovery and Preliminary Characterization of a Third Interstellar Object: 3I/ATLAS

open access: yesThe Astrophysical Journal Letters
We report initial observations aimed at the characterization of a third interstellar object. This object, 3I/ATLAS or C/2025 N1 (ATLAS), was discovered on 2025 July 1 UT and has an orbital eccentricity of e  ∼ 6.1, perihelion of q  ∼ 1.36 au, inclination
Darryl Z. Seligman   +46 more
doaj   +1 more source

OPTIMIZATION OF ENERGY COSTS AT COMBINED WITHDRAWAL OF OBJECTS SPACE DEBRIS FROM LOW EARTH ORBITS

open access: yesАвіаційно-космічна техніка та технологія, 2018
The given article is devoted one of most acute problems of use of a space – clearing of low earth orbits from space debris. As one of ways of its solution is offered withdrawal of large objects of space debris in dense layers of atmosphere of the Earth ...
Александр Вячеславович Голубек   +3 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

2023 DZ2 Planetary Defense Campaign

open access: yesThe Planetary Science Journal
We present the results of a fourth planetary defense exercise, focused this time on the small near-Earth asteroid (NEA) 2023 DZ2 and conducted during its close approach to the Earth in 2023 March.
Vishnu Reddy   +70 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Tour of Asteroids for Characterization Observations (TACO): A Planetary Defense Asteroid Tour Concept

open access: yesThe Planetary Science Journal
Asteroid impacts potentially represent a substantial threat to humanity, but one that we can plan for and mitigate. To design an effective asteroid mitigation mission, however, it is important to have as detailed knowledge of the asteroid threat as ...
Angela M. Stickle   +12 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Object Detection and Image Segmentation with Deep Learning on Earth Observation Data: A Review—Part II: Applications

open access: yesRemote Sensing, 2020
In Earth observation (EO), large-scale land-surface dynamics are traditionally analyzed by investigating aggregated classes. The increase in data with a very high spatial resolution enables investigations on a fine-grained feature level which can help us
Thorsten Hoeser   +2 more
doaj   +1 more source

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