Results 71 to 80 of about 171,503 (343)

On the Lunar Origin of Near-Earth Asteroid 2024 PT5

open access: yesThe Astrophysical Journal Letters
The near-Earth asteroid (NEA) 2024 PT5 is on an Earth-like orbit that remained in Earth's immediate vicinity for several months at the end of 2024. PT5's orbit is challenging to populate with asteroids originating from the main belt and is more commonly ...
Theodore Kareta   +4 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

OPTIMIZATION OF ENERGY COSTS AT COMBINED WITHDRAWAL OF OBJECTS SPACE DEBRIS FROM LOW EARTH ORBITS

open access: yesАвіаційно-космічна техніка та технологія, 2018
The given article is devoted one of most acute problems of use of a space – clearing of low earth orbits from space debris. As one of ways of its solution is offered withdrawal of large objects of space debris in dense layers of atmosphere of the Earth ...
Александр Вячеславович Голубек   +3 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

2023 DZ2 Planetary Defense Campaign

open access: yesThe Planetary Science Journal
We present the results of a fourth planetary defense exercise, focused this time on the small near-Earth asteroid (NEA) 2023 DZ2 and conducted during its close approach to the Earth in 2023 March.
Vishnu Reddy   +70 more
doaj   +1 more source

Object Detection and Image Segmentation with Deep Learning on Earth Observation Data: A Review—Part II: Applications

open access: yesRemote Sensing, 2020
In Earth observation (EO), large-scale land-surface dynamics are traditionally analyzed by investigating aggregated classes. The increase in data with a very high spatial resolution enables investigations on a fine-grained feature level which can help us
Thorsten Hoeser   +2 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Tour of Asteroids for Characterization Observations (TACO): A Planetary Defense Asteroid Tour Concept

open access: yesThe Planetary Science Journal
Asteroid impacts potentially represent a substantial threat to humanity, but one that we can plan for and mitigate. To design an effective asteroid mitigation mission, however, it is important to have as detailed knowledge of the asteroid threat as ...
Angela M. Stickle   +12 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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