Results 61 to 70 of about 2,370,514 (289)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Maternal Near Miss (Severe Morbidity) at Sisaket Hospital

open access: yesThai Journal of Obstetrics and Gynaecology, 2012
Objective:To study the incidence of maternal near miss cases (severe morbidity), their near miss events and obstetric outcomes at Sisaket Hospital.Materials and Methods: This prospective cross-sectional study was conducted between October 1st ...
Wanchai Wianwiset
doaj  

"Near-miss" obstetric events and maternal deaths in Sagamu, Nigeria: a retrospective study

open access: yesReproductive Health, 2005
Aim To determine the frequency of near-miss (severe acute maternal morbidity) and the nature of near-miss events, and comparatively analysed near-miss morbidities and maternal deaths among pregnant women managed over a 3-year period in a Nigerian ...
Daniel Olusoji J   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Obstetric near miss and deaths in public and private hospitals in Indonesia

open access: yesBMC Pregnancy and Childbirth, 2008
Background Falling numbers of maternal deaths have stimulated an interest in investigating cases of life threatening obstetric morbidity or near miss. The purpose of this study was to document the frequency and causes of near miss and maternal deaths in ...
Stanton Cynthia   +4 more
doaj   +1 more source

Near-miss organizational learning in nursing within a tertiary hospital: a mixed methods study

open access: yesBMC Nursing, 2022
Background Near-miss organizational learning is important for perspective and proactive risk management. Although nursing organizations are the largest component of the healthcare system and act as the final safety barrier, there is little research about
Tingting Feng   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Near miss e mulheres negras

open access: yesSaúde e Sociedade
Resumo Introdução: A mortalidade materna apresenta grande diferença entre os países desenvolvidos e em desenvolvimento e espelha a qualidade da assistência prestada à saúde da mulher.
Alaerte Leandro Martins
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Concepts, prevalence and characteristics of severe maternal morbidity and near miss in Brazil: a systematic review

open access: yesRevista Brasileira de Saúde Materno Infantil
Objectives: to analyze frequency, characteristics and causes of severe maternal morbidity (maternal near miss) in Brazil. Methods: a systematic review on quantitative studies about characteristics, causes, and associated factors on severe maternal ...
Josy Maria de Pinho da Silva   +5 more
doaj   +1 more source

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