Results 171 to 180 of about 14,002 (250)

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, EarlyView.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær, Maria Ebbesen Sørum, Silvia De Pietri, Claus Moser, Malene Johanne Petersen, Marianne Hoffmann, Henrik Hasle, Sarah Weischendorff, Klaus Müller   +8 more
wiley   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

The Effects of Nutrient Additions on Kokanee in Dworshak Reservoir, Idaho

Fisheries Management and Ecology, EarlyView.
ABSTRACT We investigated the effects of whole reservoir nitrogen (N) addition on kokanee growth in Dworshak Reservoir, Idaho. We hypothesized that N addition would improve the growth of kokanee (Oncorhynchus nerka) at a given level of abundance by increasing the availability of Daphnia, an important food source.
Sean M. Wilson, Matthew P. Corsi, Eric J. Stark, Eli A. Felts, Andrew M. Dux, Ryan S. Hardy   +5 more
wiley   +1 more source

Retention in care among women with HIV: A systematic review of treatment continuity during pregnancy and postpartum

HIV Medicine, EarlyView.
Abstract Introduction Pregnant women with HIV are at risk of reduced engagement in HIV care during pregnancy and postpartum. Retention in care, defined as continuous engagement in HIV‐related treatment and follow‐up, is essential to achieve virological suppression and prevent vertical transmission.
Stine Hansen, Klara Tetzschner Madsen, Nina Weis, Ellen Moseholm   +3 more
wiley   +1 more source

Outcomes of Kaposi sarcoma in people living with HIV who maintain long‐term viral suppression: A prospective case‐series

HIV Medicine, EarlyView.
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart, R. Palich, M. Veyri, S. Bregigeon‐Ronot, M.‐C. Picot, C. Vidal, L. Galicier, S. Choquet, J.‐P. Spano, M.‐A. Valantin, A. Makinson   +10 more
wiley   +1 more source

A multicentre evaluation of cardiovascular risk prediction tools in people living with HIV across England (ECARTH study)

HIV Medicine, EarlyView.
Abstract Introduction It remains unclear which cardiovascular disease (CVD) risk scores are optimized for people living with treated HIV with high rates of viral suppression. We evaluated the performance of commonly used CVD risk scores in a population of primarily well‐treated HIV patients in England.
Ming Jie Lee, Ashley Murray, Colette Smith, Zakee Abdi, Alastair Duncan, Ellen Dwyer, Mark Gompels, Merle Henderson, Margaret Johnson, Frances Lander, Gavin Manmathan, Jonathan Mok, Nnenna Ngwu, Coral Pratt, Iain Reeves, Razan Saman, Alice Sharp, Eleanor Taylor, Jhia Jiat Teh, Richard Stevens, Thomas R. Fanshawe, Jienchi Dorward, Ranjababu Kulasegaram, Anthony S. Wierzbicki   +23 more
wiley   +1 more source

UltRaSoUnd‐guided evaLuAtion of metabolic health in a cohort of midlife women with HIV: The URSULA study

HIV Medicine, EarlyView.
Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno, Davide Capruzzi, Antonio Cianciaruso, Nicola Colavito, Felicia Dalitto, Vincenzo Giliberti, Vittoria Lobalsamo, Giuliana Metrangolo, Marica Noviello, Alessandra Vigna, Maurizio Zarcone, Francesco Di Gennaro, Vincenzo Ostilio Palmieri, Annalisa Saracino   +13 more
wiley   +1 more source

Frailty and associated clinical factors among Japanese people with HIV: A multicentre cross‐sectional study using the revised Japanese Cardiovascular Health Study criteria

HIV Medicine, EarlyView.
Abstract Objectives Frailty is relevant to HIV care across middle and later life, yet Japanese data remain limited. We evaluated frailty, prefrailty and associated factors in Japanese people with HIV using the revised Japanese Cardiovascular Health Study (J‐CHS) criteria.
Hideta Nakamura, Julian Falutz, Taro Naka, Sho Miyamori, Nanae Ikemiyagi, Kazutaka Yamaniha, Shuhei Ideguchi, Rumi Minami, Masashi Narita, Michinori Shirano, Sei Samukawa, Tomoyuki Endo, Junji Imamura, Mayumi Imahashi, Shinichiro Ueda, Kazuko Yamamoto   +15 more
wiley   +1 more source