Results 31 to 40 of about 4,899 (168)

Surgical Removal of Residual Tumor Masses in Patients Undergoing Targeted Therapy for EGFR‐Mutated Locally Advanced or Metastatic Lung Cancer

International Journal of Cancer, EarlyView.
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko, Daniil Stroyakovskiy, Evgeniy Levchenko, Mikhail Fedyanin, Albina Gabina, Ani Oganesian, Sergey Belukhin, Maria Stepanova, Ekaterina Stepanova, Elizaveta Artemyeva, Alexander Myslik, Nikita Volkov, Alexei Bogdanov, Tatiana Shuginova, Kirill Kryukov, Valeria Kheinshtein, Arif Allakhverdiev, Ivan Zaberegniy, Yana Akhmadiyarova, Mikhail Popov, Anastasiya Danilova, Dmitriy Sehniaidze, Nikita Savelov, Nikita Levchenko, Evgeniy Slugin, Olga Lopushanskaya, Ekaterina Kuligina, Svetlana Aleksakhina, Aglaya Iyevleva, Alexandr Ivantsov, Vladimir Moiseyenko, Evgeny Imyanitov   +31 more
wiley   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

The Prognostic Value of EDRIC and Its Association With Radiation‐Induced Lymphopenia in Patients With Esophageal Cancer Undergoing Radical Radiotherapy: A Single‐Center Chinese Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the predictive value of the estimated dose of radiation to immune cells (EDRIC) in patients with esophageal cancer receiving radical radiotherapy. We retrospectively reviewed the data of patients with esophageal cancer who underwent definitive radiotherapy at our institution.
Yue Ke, Chen Yang, Yu‐Xing Li, Xiao‐Xiao Liu, Xiao Liu, Jia‐Min Gao, Hong‐Bing Ma   +6 more
wiley   +1 more source

Polarimetric Wide‐Angle Radar Detects Competing Signatures of Ice Fabric and Structural Firn Anisotropy

Geophysical Research Letters
Ice is mechanically and dielectrically anisotropic. The degree of anisotropy evolves dynamically as ice crystals align during deformation into macroscopic patterns termed ice fabric.
Falk M. Oraschewski, M. Reza Ershadi, Reinhard Drews   +2 more
doaj   +1 more source

Utility of Preoperative Cardiac Workup for Children With Very Severe Obstructive Sleep Apnea

The Laryngoscope, EarlyView.
In this retrospective study, we aimed to examine the prevalence and utility of obtaining a preoperative cardiac workup in children with very severe obstructive sleep apnea (OSA) prior to adenotonsillectomy. Of 144 patients with very severe OSA, 38 patients (26.4%) underwent a preoperative cardiac workup, and three of those 38 had abnormal findings ...
Danny A. Elias, Amber D. Shaffer, Zachary Bennett, Rachel Whelan   +3 more
wiley   +1 more source

Lumbosacral Plexopathy: A Single‐Center Review of Etiology, Clinical Presentation, Electrodiagnostic Findings, and Long‐Term Outcomes

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Lumbosacral plexopathy (LSP) results from a spectrum of etiologies and can cause substantial functional impairment. Limited data exist on the relative distribution of etiologies and outcomes across broad tertiary‐care cohorts spanning multiple causes of LSP.
Bradley Ong, Jad El Ahdab, Nicolas Thompson, Yuebing Li, Nirmal Andrapalliyal   +4 more
wiley   +1 more source

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar, Solmaz Sahebjam, Hsiang‐Husan M. Yu, Dung‐Tsa Chen, Menal Bhandari, Heiko Enderling   +5 more
wiley   +1 more source

Performance of the Earth Explorer 11 SeaSTAR Mission Candidate for Simultaneous Retrieval of Total Surface Current and Wind Vectors

Remote Sensing
Interactions between ocean surface currents, winds and waves at the atmosphere-ocean interface are key controls of lateral and vertical exchanges of water, heat, carbon, gases and nutrients in the global Earth System.
Adrien C. H. Martin, Christine P. Gommenginger, Daria Andrievskaia, Petronilo Martin-Iglesias, Alejandro Egido   +4 more
doaj   +1 more source

Sliding Mode Control in Aerospace Applications: A Survey

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT Sliding mode control (SMC) enjoys robustness to matched and unmatched (in the case of minimum phase input‐output dynamics) bounded perturbations, and finite time convergence. Second‐order and higher‐order sliding mode control systems (2‐SMC/HOSMC) retain all the advantages of sliding mode control, but in addition can be applied to systems of ...
Yuri Shtessel, Christopher Edwards
wiley   +1 more source

Dumpsite Seabed Characterization of the San Pedro Basin, CA, From Autonomous Vehicle Observations

Journal of Field Robotics, EarlyView.
ABSTRACT A wide‐area seabed survey was conducted using autonomous underwater vehicles (AUVs) in a known dumpsite off the coast of Southern California that has been found to have widespread sediment contamination from the chemical dichlorodiphenyltrichloroethane (DDT).
Ryan A. McCarthy, Dylan Kriegman, Sophia T. Merrifield, Heidi Batchelor, Eric J. Terrill   +4 more
wiley   +1 more source