Results 81 to 90 of about 2,464,680 (301)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Pathological modules over tame rings [PDF]

open access: yes, 1976
Brenner S, Ringel CM. Pathological modules over tame rings. Journal of the London Mathematical Society.
Ringel, Claus Michael, Brenner, Sheila
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The structure of balanced rings [PDF]

open access: yes, 1973
Dlab V, Ringel CM. The structure of balanced rings. Proceedings of the London Mathematical Society.
Dlab, Vlastimil, Ringel, Claus Michael
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

MODELING PROPERTIES OF INTERVAL VALUED ANTI-NEUTROSOPHIC FUZZY IDEALS IN NEAR-RINGS

open access: yesMağallaẗ Al-kūfaẗ Al-handasiyyaẗ
This paper characterizes interval-valued anti-neutrosophic fuzzy ideals (IVANFIs) within near-rings, addressing the gap in algebraic theory related to their behavior in such structures.
K. Lenin Muthu Kumaran, A. Rajalakshmi
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On the existence of nil ideals in distributive near-rings

open access: yes, 1987
In this paper we show first that the sum of the nil right ideals of a distributive near-ring N and the sum of the nil left ideals of N have the same two-sided annihilator. This ideal-here denoted by α(N)-proves useful in studying the existence of nil non-
S. Di Sieno, S. De Stefano
core   +1 more source

On the commutativity of quotient near-rings under specific identities [PDF]

open access: yesArab Journal of Mathematical Sciences
PurposeThe purpose of this paper is to investigate the commutativity of quotient near-rings endowed with a left derivation and a multiplier satisfying specific differential algebraic identities, and to clarify the role of the 3-prime condition in this ...
Slimane El Amrani, Abderrahmane Raji
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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