Results 201 to 210 of about 463,878 (344)

12‐HETE Is an Endogenous Modulator of BLT2 Triggering Vascular Degeneration, Dissection, and Rupture

open access: yesAdvanced Science, EarlyView.
In thoracic aortic dissection (TAD), elevated levels of the arachidonic acid metabolite 12‐HETE, produced by macrophage‐specific 12/15‐lipoxygenase (12/15‐LOX), bind to the BLT2 receptor on vascular cells. This activates the NOX‐1/ROS/NF‐κB signaling pathway, leading to IL‐6 release.
Yuyu Li   +13 more
wiley   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Deep Eutectic Electrolytes for Lithium Metal Batteries: A Review

open access: yesAdvanced Science, EarlyView.
Deep eutectic electrolytes (DEEs) promise next‐generation high‐energy‐density lithium (Li) metal batteries owing to their high ionic conductivity and superior safety. This review systematically summarizes the formation mechanism, properties, and application of DEEs in interface stabilization, while also outlining future directions to guide the ...
Di‐Chen Wu   +8 more
wiley   +1 more source

Activation of Molecular Oxygen by Electron‐Rich Materials for Sustainable Soil Remediation

open access: yesAdvanced Science, EarlyView.
Abundant molecular oxygen (O2) in nature can be utilized and activated by electron‐rich materials to generate reactive oxygen species for in situ engineering remediation of contaminated soil. The material types, activation mechanisms, and influencing factors are discussed in the research.
Hengxin Liu   +4 more
wiley   +1 more source

All Nanozyme‐Based Cascade Reactions for Biomedical Applications: from Self‐Cascading Nanozyme to Immobilized Cascade Nanozyme

open access: yesAdvanced Science, EarlyView.
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu   +4 more
wiley   +1 more source

Bidirectionally Thermochromic Nanocolloid System for on‐Demand Optical Switching and Agricultural Energy Management

open access: yesAdvanced Science, EarlyView.
A bidirectionally thermochromic nanocolloid system is developed for facility agriculture. The bidirectional and wide‐temperature response dynamically modulates light radiation, stabilizing the indoor climate, improving supplemental lighting efficiency, and accelerating plant photosynthesis.
Qinbo Jiang, Jiayi Li, Hui Zhang
wiley   +1 more source

The future-focused Proactive Conservation Index highlights unrecognized global priorities for vertebrate conservation. [PDF]

open access: yesPLoS Biol
de Oliveira Caetano GH   +6 more
europepmc   +1 more source

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