Results 221 to 230 of about 463,878 (344)

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao   +9 more
wiley   +1 more source

Fluorescent Probes Derived from the Polyene Class of Antifungal Drugs Reveal Distinct Localization Patterns and Resistance‐Associated Vacuolar Sequestration in Candida Species

open access: yesAngewandte Chemie, EarlyView.
Fluorescent probes derived from all three clinically used polyene antifungals (amphotericin B, nystatin, and natamycin) enabled direct visualization of distribution in yeast cells of various Candida species. While retaining the ergosterol‐dependent mode of action of their parent drugs, the probes revealed distinct, structure‐specific localization ...
Melissa Shbeta   +6 more
wiley   +2 more sources

Diversity, conservation, and endemism of the bats (Chiroptera) of Mexico. [PDF]

open access: yesZookeys
Marín-Ventura A   +4 more
europepmc   +1 more source

The collections of the two native, near threatened pteropid species in Peninsular Malaysia by the Institute for Medical Research, Malaysia: the large flying fox (Pteropus vampyrus) and island flying fox (Pteropus hypomelanus)

open access: diamond, 2021
Heng Pei Pei   +11 more
openalex   +1 more source

Radiation emergency medical countermeasures: Current formulary, identified gaps, and future approaches

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Current radiation medical countermeasures primarily focus on hematopoietic acute radiation syndrome (H‐ARS) using agents like granulocyte colony‐stimulating factor (G‐CSF), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), and romiplostim, alongside treatments for internal contamination (Prussian blue, diethylenetriamine pentaacetate [DTPA ...
Wen‐Bing Ma   +12 more
wiley   +1 more source

Floristic Composition and Species Conservation Status in Three <i>Polylepis</i> (Rosaceae) Relict Forests in Peru. [PDF]

open access: yesPlants (Basel)
Quinteros-Gómez Y   +11 more
europepmc   +1 more source

Harnessing the Neurobiology of Empathy and Compassion to Alleviate Burnout in Neurology

open access: yesAnnals of Neurology, EarlyView.
The neurologist cares for patients with complex chronic conditions that compromise their wellbeing. Many such disorders are poorly understood. Whereas for some, effective symptomatic treatments exist, for most we lack an understanding of the molecular and cellular bases for disease pathogenesis needed for discovering disease‐modifying treatments ...
Fadel Zeidan   +2 more
wiley   +1 more source

Environmental Conditions and Threatened and Endangered Species Populations near the Titain, Atlas, and Delta Launch Complexes, Cape Canaveral Air Station

open access: green, 1999
Donna M. Oddy   +6 more
openalex   +1 more source

Antibacterial Applications of Black and Violet Phosphorus‐Based Biomaterials

open access: yesAdvanced NanoBiomed Research, EarlyView.
Black and violet phosphorus‐based biomaterials exhibit broad‐spectrum antibacterial efficacy in various infections, including bone, skin, ocular, dental, lung, and sepsis cases. Their antibacterial mechanisms include physical disruption, light‐driven effects, targeted drug delivery, and enhanced composite strategies.
Zhuo Dai   +8 more
wiley   +1 more source

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