Results 91 to 100 of about 537,161 (304)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Some considerations on pitch [PDF]
Pitch is an audible quality of sound which can be explained not only in terms of strong correlation with sound waves’ properties, but also by a neat correlation to the properties of the sounding object.
Di Bona, E.
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Functionalized multiwalled carbon nanotubes (F-MWCNTs)/Co–Ti oxide nanocomposites and neat Co–Ti oxide nanoparticles were synthesized by chemical reduction method.
Noor Zada, Khalid Saeed, Idrees Khan
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The NOMAD system : expectation-based detection and correction of errors during understanding of syntactically and semantically ill-formed text [PDF]
Most large text-understanding systems have been designed under the assumption that the input text will be in reasonably "neat" form (for example, newspaper stories and other edited texts).
Granger, Richard H.
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Preliminary properties of a resin from ethynyl terminated materials [PDF]
A blend composed of an ethynyl terminated aspartimide (brittle component) and an ethynyl terminated arylene ether oligomer (tough component) was thermally cured to yield a resin which underwent preliminary evaluation to determine the potential for use in
Connell, John W., Hergenrother, Paul M.
core +1 more source
Emulsifaction of waste cooking oils and fatty acid distillates as diesel engine fuel [PDF]
The scope of this paper is to analyze the possibilities and feasibilities, as well as the main experimental results reported about the emulsification method applied to waste cooking oils and fatty acid distillates as diesel engine fuels, compared with ...
Goyos-Pérez, Leonardo +3 more
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source

