Results 91 to 100 of about 537,161 (304)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Some considerations on pitch [PDF]

open access: yes, 2013
Pitch is an audible quality of sound which can be explained not only in terms of strong correlation with sound waves’ properties, but also by a neat correlation to the properties of the sounding object.
Di Bona, E.
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Decolorization of Rhodamine B dye by using multiwalled carbon nanotubes/Co–Ti oxides nanocomposite and Co–Ti oxides as photocatalysts

open access: yesApplied Water Science, 2019
Functionalized multiwalled carbon nanotubes (F-MWCNTs)/Co–Ti oxide nanocomposites and neat Co–Ti oxide nanoparticles were synthesized by chemical reduction method.
Noor Zada, Khalid Saeed, Idrees Khan
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The NOMAD system : expectation-based detection and correction of errors during understanding of syntactically and semantically ill-formed text [PDF]

open access: yes, 1983
Most large text-understanding systems have been designed under the assumption that the input text will be in reasonably "neat" form (for example, newspaper stories and other edited texts).
Granger, Richard H.
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Preliminary properties of a resin from ethynyl terminated materials [PDF]

open access: yes
A blend composed of an ethynyl terminated aspartimide (brittle component) and an ethynyl terminated arylene ether oligomer (tough component) was thermally cured to yield a resin which underwent preliminary evaluation to determine the potential for use in
Connell, John W., Hergenrother, Paul M.
core   +1 more source

Emulsifaction of waste cooking oils and fatty acid distillates as diesel engine fuel [PDF]

open access: yes, 2015
The scope of this paper is to analyze the possibilities and feasibilities, as well as the main experimental results reported about the emulsification method applied to waste cooking oils and fatty acid distillates as diesel engine fuels, compared with ...
Goyos-Pérez, Leonardo   +3 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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