Results 91 to 100 of about 116,309 (264)
Deliverable D1.1 - NEAT Architecture [Elektronisk resurs]
, 2016 Ossification of the Internet transport-layer architecture is a significant barrier to innovation of the Internet. Such innovation is desirable for many reasons.
Welzl, Michael, +16 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Innovative nano-electrode chip for electroporation in yeast
Materials Today AdvancesElectroporation is a widely used technique for gene transfection, protein expression, and cellular labeling, but conventional electroporation approaches typically require high-voltage pulses that induce Joule heating, reduce cell viability, and yield ...
Hsiao-Chi Chen +3 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The regimental pet [music] : (Drummer boy) /
, 1907 For voice and piano.; Cover title.; "Featured with great success in Williamson's pantomime, Humpty Dumpty, by Miss Florence Young."; "This song may be sung in public fee or license except at theatres & music halls."; Library's N copy imprint covered by ...
Neat, John.
core
Frontiers in Sports and Active LivingAthletes experience high total energy expenditure; therefore, it is important to understand the characteristics of the components contributing to this expenditure.
Mika Goshozono +4 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The regimental pet (Drummer boy) [music] /
, 1907 Feldman's sixpenny editions; no.195 (Publisher number). For voice and piano.; "Featured with great success in Williamson's pantomime, Humpty Dumpty, by Miss Florence Young"; This song may be sung in public fee or license except at theatres & music halls -
Neat, John.
core