Results 141 to 150 of about 116,309 (264)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Neat exact sequences of abelian groups

, 1995
oz Değişmeli bir grubun alt grubunun her elemanının herhangi bir asal sayı tarafından bölünebilirliği, elemanın bu asal sayı tarafından alt grupta da bölünebilirliği sonucunu veriyorsa bu alt gruba neat altgrup denir. Neat olma durumu pure olma durumunun
GÖKHAN BİLHAN
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Eutectic Itraconazole and Posaconazole System and the Advantages of Its Use in the Amorphous Form. [PDF]

Mol Pharm
Knapik-Kowalczuk J, Serajuddin ATM, Poloczek P, Mathew M, Cichocka-Łokuciejewska J, Paluch M.   +5 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Reproductive allocation in Aidablennius sphynx (Teleostei: Blenniidae): females lay more eggs faster when paired to larger males

, 2005
F.C. Neat, LOCATELLO, LISA
core   +1 more source

Investigating the Crystallization Kinetics and Mechanical Properties of Poly(Butylene Succinate): The Dual Role of Polyoxymethylene Blending and MWCNT Heterogeneous Nucleation. [PDF]

Polymers (Basel)
Tutuş C, Yıldırım R, Yazıcı Çakır N, Gökmen M, Özkoç G, Kodal M.   +5 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Running Distance Is Associated With Components of Total Energy Expenditure in Amenorrhoeic and Non-Amenorrhoeic Endurance Runners. [PDF]

Scand J Med Sci Sports
Uchizawa A, Kondo E, Enomoto Y, Yajima K, Tamai S, Watanabe K, Ito A, Kosugi M, Higaki Y, Sagayama H.   +9 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source