Results 201 to 210 of about 14,058 (258)

Role of p38 MAPK, Akt and NFκB in renoprotective effects of nebivolol on renal ischemia-reperfusion injury in rats

Biotechnic & Histochemistry, 2023
Renal ischemia-reperfusion (I-R) injury is a complex pathophysiologic condition characterized by oxidative stress, inflammation and apoptosis. We investigated the potential renoprotective effect of nebivolol, a β1 adrenergic receptor blocker, against ...
Z. Çavdar, A. Koçak, Cemre Ural, Aysan Afagh, S. Ersan, S. Ozbal, Merve Tatli, A. Celik, Ş. Arslan, C. Çavdar   +9 more
semanticscholar   +1 more source

Nebivolol and incident cardiovascular events in hypertensive patients compared with nonvasodilatory beta blockers

Journal of Hypertension, 2022
Objective: Nonvasodilatory beta blockers are associated with inferior cardiovascular event reduction compared with other antihypertensive classes, and there is uncertainty about first-line use of beta blockers for hypertension in guidelines.
D. Huck, M. Rosenberg, B. Stauffer
semanticscholar   +1 more source

Nebivolol protects erectile functions compared to Metoprolol in hypertensive men with atherogenic, venogenic, psychogenic erectile dysfunction: A prospective, randomized, cross-over, clinical trial.

European journal of internal medicine, 2022
INTRODUCTION Both hypertension and β-blocker drugs used for treating hypertension (HT) can cause erectile dysfunction (ED). Nebivolol, unlike other β-blockers, may not cause impotence since it increases the release of Nitric Oxide (NO), which is the main
G. Gungor, H. Perk, S. Soyupek, Bahattin Baykal, M. Demir, M. Sezer   +5 more
semanticscholar   +1 more source

Design of new boron-doped carbon dots for nano-level assay of nebivolol in human plasma and commercial products; Application to greenness assessments.

Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy
Recently, nanomaterials have attracted a lot of attention due to their potential as effective fluorescent nano-sensor probes. They were distinguishing substitutes for other luminescent techniques, such as fluorescent dyes and luminous derivatization ...
H. AlSalem, S. N. Alharbi, S. T. Al-Goul, Baher I. Salman, Y. F. Hassan, Mohamed A. Abdel-Lateef   +5 more
semanticscholar   +1 more source

Development and Validation of an Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry method with Liquid-Liquid Extraction for The Quantification of Sitagliptin in Human plasma using Nebivolol as Internal Standard

Research Journal of Pharmacy and Technology, 2022
We aimed to investigate the performance of the development method for sitagliptin quantification analysis in human plasma by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS) using liquid-liquid extraction (LLE) and Nebivolol as ...
Henny Rochaeny, Candra Irawan, Ismail Dwi Saputro, Lintannisa Rahmatia, Nilna Izzatul Mawaddah   +4 more
semanticscholar   +1 more source

Development and Validation of UV Absorbance Ratio Method for the Simultaneous Estimation of Nebivolol and Valsartan in Bulk Drugs and Pharmaceutical Dosage Form

Research Journal of Engineering and Technology, 2022
A simple, robust, precise, UV spectroscopic method has been developed for the simultaneous estimation of Nebivolol and Valsartan in bulk and tablet dosage forms. In this paper the estimation of those drugs was carried out by simultaneous equation method.
Rajesh Y. Chaudhari, Sachin S. Rane, Mahesh S. Nemade   +2 more
semanticscholar   +1 more source

Enhanced eNOS/nitric oxide production by nebivolol interferes with TGF-β1/Smad3 signaling and collagen I deposition in the kidney after prolonged tacrolimus administration.

Life Science
AIMS Tacrolimus is an effective immunosuppressant commonly used post-transplantation and in certain autoimmune diseases. However, its long-term administration is associated with renal fibrosis through transforming growth factor-beta/suppressor of mother ...
Amany A. Azouz, M. Tohamy, Fares E. M. Ali, Heba M. Mahmoud   +3 more
semanticscholar   +1 more source

Nebivolol protects against cyclophosphamide‐induced nephrotoxicity through modulation of oxidative stress, inflammation, and apoptosis

Clinical and Experimental Pharmacology and Physiology, 2021
The usefulness of cyclophosphamide (CP) in the treatment of multiple human malignancies and immunological diseases is hindered by the danger of developing nephrotoxicity.
Hanna Wanas, Mohamed El-Shabrawy, Amal A. Mishriki, Hisham Attia, M. Emam, B. Aboulhoda   +5 more
semanticscholar   +1 more source

Effect of nebivolol on erectile function: a systematic review and meta-analysis of randomized controlled trials.

Journal of Sexual Medicine
BACKGROUND Historically, β-blockers have been associated with erectile dysfunction (ED). Nebivolol, a third-generation β-blocker, may have had no negative effect on erectile function because of its vasodilating properties. However, the evidence level was
Youyi Lu, Lin Li, Qi Li, G. Sun
semanticscholar   +1 more source

[Clinical pharmacology of nebivolol].

Cardiologia (Rome, Italy), 1999
Nebivolol is a novel, potent and highly selective beta(1)-adrenergic antagonist, devoid of intrinsic sympathomimetic activity, that induces endothelium-dependent arterial and venous dilatation via the L-arginine-nitric oxide pathway. Nebivolol reduces blood pressure and peripheral vascular resistance and does not depress, but rather maintains or ...
ROSSI, Francesco, D'AMICO, Michele, ROSSI, Settimio   +2 more
openaire   +5 more sources