Results 141 to 150 of about 118,017 (304)

Divergent c-MYC Expression Patterns in NET and NEC: Insights from a Multicentre Cohort of 1380 Neuroendocrine Neoplasms. [PDF]

Endocr Pathol
Schmitt M, Ofner K, Bartsch DK, Wagner DC, Rinke A, Gress T, Kremer M, Evert M, Reitsam NG, Koberova V, Märkl B, Quaas A, Eckstein M, Steinestel K, Pagenstecher A, Keber U, Denkert C, Steiger K, Foersch S, Klöppel G, Kasajima A, Bohnenberger H, Jesinghaus M.   +22 more
europepmc   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Multiomics analyses revealed the roles of the epithelial-mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis. [PDF]

Clin Transl Med
Liu XC, Liu GB, Cheng C, Zhu J, Chen FF, Ji Y, Zhang YN, Yan XL, Wang Q, Li XY, Ai Q, Shi Y, He Y.   +12 more
europepmc   +1 more source

m6A‐Related Regulation of Ferroptosis Contributes to Nasal Epithelial Barrier Dysfunction in Allergic Rhinitis

Allergy, EarlyView.
This study uses human nasal epithelial cells and BALB/c mice to evaluate the role and molecular mechanism of ferroptosis in HDM‐induced AR, focusing on ferroptosis‐related responses and nasal epithelial barrier disruption. HDM exposure induces lipid peroxidation‐driven ferroptosis and epithelial barrier disruption.
Zehua Lin, Baoai Han, Qiang Xie, Aikebaier Tuohuti, Weisong Cai, Peng Zhou, Jiahao Meng, Qiuyang Fu, Zuhong He, Xiong Chen   +9 more
wiley   +1 more source

Immunological Features of Neuroendocrine Neoplasms and Adrenal Tumors. [PDF]

Cancer Med
Ohmoto A, Takahashi S, Kitano S.
europepmc   +1 more source

THESS‐ROP study: Development of a prediction model for treatment‐warranted retinopathy of prematurity and external validation of postnatal weight‐gain‐based models in Greece

Acta Ophthalmologica, EarlyView.
Abstract Purpose To develop THESS‐ROP, a novel prediction model for treatment‐warranted retinopathy of prematurity (TW‐ROP) and compare its performance with four established models in a Greek cohort of consecutively screened preterm infants. Methods This ambispective cohort study included all 526 infants screened for ROP (2016–2022) at the 2nd ...
Stella Moutzouri, Anna‐Bettina Haidich, Maria Lithoxopoulou, Georgios Pappas, Christos Tsakalidis, Nikolaos Ziakas, Asimina Mataftsi   +6 more
wiley   +1 more source

ROS-Dependent GSDMD Activation Drives Intestinal Pyroptosis in Neonatal Necrotizing Enterocolitis (NEC). [PDF]

Cell Biol Int
Ye C, Luo J, Liu X, Ma Y, Yang X, Mo D, Deng Q, Ding X, Guo C.   +8 more
europepmc   +1 more source

Immune System Development—Pro Tips for Paediatricians

Acta Paediatrica, EarlyView.
ABSTRACT There are many misconceptions about the immune system in children, its impact on infectious disease susceptibility and its role in the rapidly increasing rates of immune mediated diseases in industrialized societies. In this mini review, I will discuss common believes and the data supporting or countering such believes, with a focus on ...
Petter Brodin
wiley   +1 more source

Hyperglycemia 72 h before necrotizing enterocolitis onset and mortality among premature and term infants in Kenya. [PDF]

PeerJ
Muhia M, Ochieng R, Migowa A.
europepmc   +1 more source

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source