Results 171 to 180 of about 573,097 (333)

Immunohistochemistry as a tool for identifying EGFR amplification in CNS tumors

Brain Pathology, EarlyView.
EGFR gene amplification constitutes a diagnostic hallmark for glioblastoma, IDH‐wildtype (GB, IDH‐WT). Herein, we demonstrated that EGFR IHC is a highly specific and sensitive biomarker for identifying EGFR amplification and should be part of the neuropathologist's routine panel of antibodies.
Arnault Tauziède‐Espariat, Mary Bah, Farah Sassi, Noémie Pucelle, Charlotte Berthaud, Marion Mandoula, Zeina Dababou, Noah Carnes, Leïla Brissez, Lauren Hasty, Euphrasie Servant, Alice Métais, Pascale Varlet   +12 more
wiley   +1 more source

OGSA/Globus Evaluation for Data Intensive Applications

, 2003
We present an architecture of Globus Toolkit 3 based testbed intended for evaluation of applicability of the Open Grid Service Architecture (OGSA) for Data Intensive Applications.Comment: To be published in the proceedings of the XIX International ...
Da Rocha, R. B., Demichev, A., Foster, D., Kalyaev, V., Kryukov, A., Lamanna, M., Pose, V., Wang, C.   +7 more
core   +1 more source

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

British Journal of Pharmacology, EarlyView.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini, Patrizia Nardini, Virginia Zizi, Marta Molino, Maura Calvani, Francesco Carrozzo, Rachele Amato, Daniele Guasti, Denise Biagini, Fabio di Francesco, Ludovico Silvestri, Alessandra Franceschini, Daniele Bani, Elisa Imbimbo, Luca Filippi   +14 more
wiley   +1 more source

Non-linear error correction, asymmetric adjustment and cointegration. [PDF]

This article links the intertemporal choice model with the non-linear error correction (NEC) model. It has three main components. First, it outlines a model of non-linear error correction, in which the linear error correction term ?Xt (the vector time ...
Escribano, Álvaro, Pfann, Gerard
core  

Atezolizumab + Chemotherapy for Advanced Non‐Small Cell Lung Cancer in Japanese Clinical Practice (J‐TAIL‐2)

Cancer Science, EarlyView.
The J‐TAIL‐2 prospective, observational study evaluated atezolizumab combined with several chemotherapy regimens in patients with advanced/metastatic non‐small cell lung cancer in routine clinical practice in Japan. The real‐world efficacy and safety of each atezolizumab combination were found to be comparable to those seen in the relevant global ...
Hiroshige Yoshioka, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Yasushi Goto, Junichi Shimizu, Eisaku Miyauchi, Ichiro Yoshino, Toshihiro Misumi, Yasutaka Watanabe, Akito Hata, Akira Kisohara, Shoichi Kuyama, Masafumi Yamaguchi, Asako Miwa, Shunichiro Iwasawa, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study.

Annals of Oncology, 2013
H. Sørbye, S. Welin, S. Langer, L. Vestermark, N. Holt, P. Österlund, S. Dueland, E. Hofsli, M. Guren, K. Öhrling, Elke Birkemeyer, E. Thiis-Evensen, Matteo Biagini, H. Grønbæk, L. Soveri, I. Olsen, B. Federspiel, J. Assmus, E. T. Janson, U. Knigge   +19 more
semanticscholar   +1 more source

Tier 2 adult weight management services in the UK: A case study evaluation of local authority provision of targeted services for higher‐risk groups in England

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary In 2021, the UK Government announced additional funding in England for Adult Weight Management Services (AWMS); it was specified that the extra funding must be used to commission or extend existing tier 2 services. The Office for Health Improvement and Disparities encouraged commissioners to prioritise services for higher‐risk groups such as ...
Lorraine McSweeney, Charlotte Rothwell, Ashley Adamson, Simon Barrett, Claire Mathews, Scott Lloyd, Mackenzie Fong   +6 more
wiley   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Nec bene cum nec sine illis

, 2012
Source: Ludwig Eichrodt: Leben und Liebe, Frankfurt a.M.: Heinrich Keller, 1856.
openaire   +1 more source

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, EarlyView.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source