Results 271 to 280 of about 573,097 (333)

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

open access: yesCancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao   +38 more
wiley   +1 more source

KLF1 Exerts Pro‐Tumour Role in Liver Cancer via Inhibiting ACSL4/LPCAT3‐Regulated Ferroptosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Kruppel‐like factors (KLFs) constitute a crucial family of transcription factors that are engaged in a variety of biological processes, such as erythropoiesis as well as liver development. A growing body of research underscores the increasing importance of the KLF family in the context of hepatocellular carcinoma (HCC). Despite this, the exact
Zhihui Chen   +3 more
wiley   +1 more source

Age‐Specific Diagnostic Panorama Among People With Intellectual Disabilities in Comparison With the General Population: A Longitudinal Register Study (IDcare)

open access: yesJournal of Intellectual Disability Research, Volume 70, Issue 3, Page 295-315, March 2026.
ABSTRACT Background People with intellectual disabilities (ID) are known to have a higher risk for a wide range of health conditions compared to the general population. However, there is little research comparing a more comprehensive range of diseases and conditions at different ages.
Magnus Sandberg   +2 more
wiley   +1 more source

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