Results 151 to 160 of about 4,848 (199)
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Antibody responses in self-infections with Necator americanus
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1978Antibody responses were measured in a volunteer infected four times with Necator americanus over a 27-month period. The main source of antigen was culture fluid in which living adult N. americanus had been maintained for several days. Antibodies to worm acetylcholinesterase and IgE antibodies were detected only with this material, but antibodies were ...
B M, Ogilvie +5 more
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Necator americanus Infection in Primates
The Journal of Parasitology, 1971Laboratory-bred and feral chimpanzees (Pan troglodytes) and young, laboratory-bred, patas monkeys (Erythrocebus patas) exposed to infective larvae of Necator americanus cultured from human feces developed patent infections in 42 to 54 days; adult, feral patas monkeys were refractory to infec- tion.
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Necator americanus: Behaviour in hamsters
Experimental Parasitology, 1972Abstract The human hookworm, Necator americanus originally isolated from a patient was serially passed in golden hamsters over a period of 4 years. The parent and four succeeding populations were passed in these animals under cortisone. Adaptation of these parasites to the hamster occurred from the sixth serial passage and thereafter following the ...
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The immunogenicity of hookworm (Necator americanus) acetylcholinesterase (AChE) in man
Parasite Immunology, 1993SummaryA number of different but complementary approaches have been used to demonstrate the immunogenicity of Necator americanus acetylcholinesterase to infected individuals. Western blotting of parasite somatic extracts with human postâinfection sera and a specific rabbit antiserum to AChE resulted in the development of almost identical antigen ...
David I Pritchard
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Radioactive tagging of hookworm larvae (Necator americanus) with P32
Experimental Parasitology, 1958Abstract Larvae of Necator americanus were successfully tagged with P32 by cultivation of the larvae through the free-living stages in the presence of the isotope. The degree of absorption of P32 by the larvae was influenced by the strength of P32 in the cultures, the addition of bacteria previously activated, and by the nature of the medium for ...
G A, DISSANAIKE +2 more
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Identification of hookworm (Necator americanus) antigens and their translation in vitro
Molecular and Biochemical Parasitology, 1986During in vitro culture adult (day 35) Necator americanus synthesise a wide range of protein species many of which are excreted or secreted into the culture medium. Both post infection (day 117) hamster sera and sera from infected humans precipitate antigens of 15, 30, 33, 44, 46 and 69 kDa although individual human sera exhibit some variability in ...
A, Carr, D I, Pritchard
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Genes and genomes of Necator americanus and related hookworms
International Journal for Parasitology, 2000The human hookworms (Necator americanus and Ancylostoma duodenale) infect over one billion people. The phylogenetic relationships of the human hookworms suggest independent acquisition of the human host. The hookworms probably have a haploid chromosome number n = 6, and an XX-XO sex determination mechanism is likely to be used.
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A simple method for the collection of Necator americanus larvae
Journal of Helminthology, 1989ABSTRACTA simple method for the collection of third-stage larvae of Necator americanus has been described. This technique provides repeated recovery of very clean larvae from cultures in moderate numbers.
J, Mueller +4 more
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The specificity of the human IgE response to Necator americanus
Parasite Immunology, 1995SUMMARYHuman IgE responses to helminth infections have been described as both problematic and beneficial, in that type 1 hypersensitivity to parasite infections can reputedly cause pathology and/or parasite expulsion, (Pritchard, Quinnell & Walsh 1995).
D I, Pritchard, E A, Walsh
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Hookworm (Necator americanus) infection and storage iron depletion
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991The relationship between iron status and the intensity of infection with hookworm was investigated in a rural population on Karkar Island, Mandang Province, Papua New Guinea. There was a significant negative correlation between plasma ferritin level and hookworm burden, which was strongest in males.
Pritchard, D. I. +7 more
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