Results 31 to 40 of about 992,473 (296)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Bougie-facilitated Intubation in Penetrating Neck Injury
Eurasian Journal of Emergency Medicine, 2019 A young male patient with a history of schizophrenia was admitted to the emergency department after suicide attempt. He slashed his neck with a broken glass and this resulted in a wound in zone II exposing laryngeal structures.
Ahmad Wazzan
doaj +1 more source
Africa: A window on challenges and opportunities for head and neck cancer
Laryngoscope Investigative Otolaryngology, 2021 Background Head and neck cancer occurs predominantly in the Developing World, with significant challenges relating to a high burden of disease, late presentation, and poor access to curative and palliative care.
Johannes J. Fagan
doaj +1 more source
Antibiotic Resistance Pattern in Pediatric Deep Neck Space Infection
International Archives of Otorhinolaryngology, 2022 Introduction Neck space infection in the pediatric age group is common but can be life-threatening if not diagnosed properly. Since it is a polymicrobial disease, antibiotic usage should be guided by culture sensitivity pattern.
Bijaya Kharel +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Effect of acupuncture on the molar bite force in women with chronic neck pain
Journal of Oral Research, 2023 Objetive: To investigate the maximum molar bite force in women with chronic neck pain after treatment with acupuncture. Materials and Methods: Twenty-three women with chronic neck pain participated.
Odinê Rêgo Bechara +4 more
doaj +1 more source
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Managing the airway of acid burn contracture of the neck in a 12-year-old girl
Journal of the Scientific Society, 2020 Managing the airway of patient with postburn contracture at the neck is often challenging for otolaryngologists and anesthesiologists. It affects the oro-pharyngo-laryngeal airway axes because of anatomical and functional deformities because of the long ...
Santosh Kumar Swain, Nibi Shajahan
doaj +1 more source