Results 101 to 110 of about 966,989 (400)
Foregoing elective neck dissection for elderly patients with oral cavity squamous cell carcinoma [PDF]
, 2023 Nir Tsur +7 more
openalex +1 more source
Advanced Science, EarlyView.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
A safe transoral surgical approach to parapharyngeal tumor arising from deep lobe of parotid gland [PDF]
, 2016 The management of parapharyngeal tumor is surgical, but the approach remains a challenge. Attention should be paid to avoidance intra-operative bleeding or cranial nerves damage. We report a case of a 67-year-old male complaining of left-ear fullness.
Capuano, Francesco +7 more
core +2 more sources
World Journal of Surgical Oncology, 2016 BackgroundLymph nodal involvement is very common in differentiated thyroid cancer, and in addition, cervical lymph node micrometastases are observed in up to 80 % of papillary thyroid cancers.
C. Gambardella +13 more
semanticscholar +1 more source
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Advanced Science, EarlyView.Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
The Role of Prophylactic Central Neck Dissection in the Treatment of Differentiated Thyroid Cancer
Rambam Maimonides Medical Journal, 2016 The utility and efficacy of prophylactic central neck dissection with total thyroidectomy for the treatment of differentiated thyroid cancer has been debated in the literature over the past few decades.
Max Hennessy, David Goldenberg
doaj +1 more source
Advanced Science, EarlyView.This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang +14 more
wiley +1 more source
Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]
, 2013 Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher +3 more
core +1 more source
Advanced Science, EarlyView.Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu +21 more
wiley +1 more source