Results 121 to 130 of about 657,615 (256)

Single‐Cell Profiling Identifies SLC2A5‐Mediated Fructose Metabolism as a Vulnerability in Primary CNS Lymphoma

Advanced Science, EarlyView.
Glucose deprivation in the primary CNS lymphoma (PCNSL) tumor microenvironment drives SLC2A5 (encoding GLUT5)‐dependent fructose metabolism in tumor cells, while hypoxia induces HIF‐mediated SLC2A5 expression in tumor‐supportive macrophages, revealing SLC2A5‐driven fructose utilization as a shared and targetable metabolic vulnerability across malignant
Qiaoli Wu, Qianru Zhang, Wenqiang Yan, Lu Sun, Yiran Cui, Bolin Liu, Guoqing Han, Feng Zhang, Ke Pu, Mingchao Zhang, Xiaobing Zhang, Qingguo Li, Gang An, Yuxuan Liu   +13 more
wiley   +1 more source

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

Advanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia, Lei Liu, Shuang Jin, Guangxu Fang, Chang Yu, Yunyun Wu, Lunli Xiang, Hongrui Zhu, Zhenqiang Wang, Jixi Zhang   +9 more
wiley   +1 more source

Hemothorax caused by zone I penetrating neck injury effectively treated with pleural dome laceration covering performed using video-assisted thoracic surgery: a case report

Journal of Medical Case Reports
Background Penetrating neck injuries in the area between the clavicles and the cricoid cartilage sometimes cause intrathoracic problems such as pneumothorax or hemothorax.
Sachie Koike, Takayuki Shiina, Keiichirou Takasuna   +2 more
doaj   +1 more source

Penetrating Neck Trauma with Bilateral Pneumothorax and Pneumomediastinum: A Case Report and Review of Literature

Journal of Advanced Lung Health
Penetrating neck trauma presents a complex and challenging scenario in clinical practice. We present the case report of a 31-year-old male who suffered a neck injury due to a small iron rod piercing the anterior aspect of the neck in a road traffic ...
Nasma Mankara Thodi, Rinoop Ramachandran, Fabith Moideen   +2 more
doaj   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Near Side Crash Neck Injury, Crash Test and Accident data comparison

International Journal of Automotive Engineering
Near side crashes make up high mortality and serious injury rates. Side airbags protect vehicle occupants in near side crashes. In previous reports, the author analyzed the effect of side airbags and found that the effect of the torso protection side air
Kazuo Higuchi
doaj   +1 more source

[Neck injuries].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1992
Diagnostic work-up of neck injuries is dependent on vital signs, neurologic status and location of the wound. Patients who are haemodynamically unstable, who exhibit current arterial bleeding, expanding or pulsatile haematoma or respiratory distress after initial resuscitation are taken to the operating theatre without further delay.
L, Rosén, J A, Weigelt, K L, Mattox
openaire   +1 more source

Disputatio inauguralis continens quaestiones miscellaneas ex iure civili, canonico, feudali, et publico depromptas

quam ... pro summo in utroque iure gradu, privilegiis ac honoribus doctoralibus impetrandis publicè, horis locoque consuetis, discutiendam proponit Nicolaus Neck Horna-Batavus, ad diem Octobr. anno MDCXXXII.Druckjahr nach der Datierung im TitelEnthält 32
Neck, Nicolaus
core   +1 more source

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

Advanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang, Jiayun Wang, Junjie Lin, Ziping Ye, Geyujia Zhou, Jingjing Ma, Junjian Sun, Jiang Yu, Yingdi Zhang, Nana Tang, Chunhua Jiao, Xiaojing Zhao, Hongjie Zhang   +12 more
wiley   +1 more source