Results 101 to 110 of about 55,005 (210)

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

BACE2 Promotes Bladder Cancer Chemoresistance Through Proteolytic Activation of JAG1‐Notch Signaling

open access: yesCancer Innovation, Volume 5, Issue 4, August 2026.
Proposed model of β‐secretase 2 (BACE2)‐mediated chemoresistance in bladder cancer. In BACE2‐low bladder cancer cells (left), the Notch signaling axis remains silenced, rendering cells highly sensitive to chemotherapy. In BACE2‐high cells (right), BACE2 mediates cleavage of transmembrane Jagged1 (JAG1) to release soluble JAG1 (sJAG1).
Zekun Li   +4 more
wiley   +1 more source

Circulating Mitochondrial DNA Measures Across Malignancies: Diagnostic Accuracy and Prognostic Associations

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Circulating mitochondrial DNA is being investigated as a liquid‐biopsy biomarker because of its high copy number and release during cellular stress. However, diagnostic estimates vary across tumor types and assays, and prognostic studies have measured both cell‐free mtDNA and cellular blood‐derived mtDNA, which are not analytically ...
Ziying Zhang   +5 more
wiley   +1 more source

A Comprehensive Meta‐Analysis and Review of Intraoperative Radiotherapy in Colorectal Cancer: Examining Radiation Dosage, Long‐Term Prognosis, and Treatment‐Related Complications

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background The effect of device type and radiation dose in intraoperative radiotherapy (IORT) for colorectal cancer is not well established. To explore this, we reviewed studies reporting postoperative complications, disease‐free survival, local control, and long‐term survival in patients treated with non‐implantable IORT techniques—IOERT, KV ...
Chuhan Guo   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy