Results 181 to 190 of about 645,902 (311)

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Eagle syndrome as a rare cause of recurrent neck pain: a case report. [PDF]

Arch Craniofac Surg
Aragone L, Silva AD, Zeballos G, Adan R, Berenstein B.   +4 more
europepmc   +1 more source

TARDBP (TDP‐43) Knock‐in Zebrafish Display a Late‐Onset Motor Phenotype and Loss of Large Spinal Cord Motor Neurons

Annals of Neurology, EarlyView.
Objective Mutations in TARDBP (encoding TDP‐43) are associated with the neurodegenerative disease amyotrophic lateral sclerosis (ALS) and include familial missense mutations where there are a lack of models and mechanisms examining how they are pathogenic.
Ziyaan A. Harji, Christian J. Rampal, Esteban C. Rodríguez, Virginie Petel Légaré, Alexandra Lissouba, Sabrina Semmler, Meijiang Liao, Jay P. Ross, Guy A. Rouleau, Christine Vande Velde, Gary A.B. Armstrong   +10 more
wiley   +1 more source

Neck pain and emotional state in cervical spondylosis: A dual trajectory model analysis. [PDF]

World J Psychiatry
Yang JQ, Wu J, Guo JE, Yang ZX, Liu JY, Wang YM, Zhang YJ.   +6 more
europepmc   +1 more source

Referrals to the specialist health service for patients with neck or back pain [PDF]

John Bjørneboe, Jostein Skranes Brox, Kjersti Myhre, Mirad Taso, Erik L. Werner, Cecile Røe, Jens Ivar Brox   +6 more
openalex   +1 more source

Behavior Decoding Delineates Seizure Microfeatures and Associated Sudden Death Risks in Mouse Models of Epilepsy

Annals of Neurology, EarlyView.
Objective Behavior and motor manifestations are distinctive yet often overlooked features of epileptic seizures. Seizures can result in transient disruptions in motor control, often organized into specific behavioral sequences that can inform seizure types, onset zones, and outcomes.
Yuyan Shen, Jaden Thomas, Xianhui Chen, Jaden Zelidon, Mariam Najeeb, Abigayle Hahn, Ping Zhang, Aaron Sathyanesan, Bin Gu   +8 more
wiley   +1 more source

Associations between social factors and spinal pain-related disability in people with back pain and/or neck pain. [PDF]

Ann Med
Bijker L, Ten Have M, Scholten-Peeters GGM, Coppieters MW, Cuijpers P, de Wit LM.   +5 more
europepmc   +1 more source

From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective The growing demand for personalized treatment in multiple sclerosis (MS) highlights the need for more precise biomarkers that can outperform magnetic resonance imaging and clinical assessment in patient stratification. Advances in multiplex proteomic technologies suggest that cerebrospinal fluid (CSF) analysis at MS onset may not only improve
Laura Ghezzi, Peter Kosa, Mark Greenwood, Enrique Alvarez, C.L. Freedman, Anne H. Cross, Francesca Pace, Mark S. Freedman, Joanna Kocot, Laura Piccio, Bibiana Bielekova   +10 more
wiley   +1 more source

Gatekeepers in primary care - a qualitative study on manual therapists' role in triaging patients with back and neck pain. [PDF]

BMC Health Serv Res
Axén I, Schriwer E, Hjertstrand J, Skillgate E, Palmgren PJ, Eklund A.   +5 more
europepmc   +1 more source

The Effects of Cervical Spine Mobilization versus Manipulation on Pain, Disability, and Satisfaction in Subjects with Non-specific Mechanical Neck Pain

Alfredo Loreto, Everett Lohman, Lida Gharibvand, Trevor Lohman, Lee Berk   +4 more
openalex   +1 more source