Hydrogen Peroxide Flushes for Necrotizing Pancreatitis in a High-Risk Surgical Patient: A Pathway for Durable Response Without Additional Endoscopic Intervention [PDF]
Necrotizing pancreatitis (NP) is characterized by severe pancreatic inflammation with necrosis and a systemic inflammatory response. We describe the case of a 32-year-old female with NP successfully treated with a modified protocol using hydrogen ...
Smriti Kochhar +2 more
doaj +2 more sources
Open Surgical versus Minimal Invasive Necrosectomy of the Pancreas-A Retrospective Multicenter Analysis of the German Pancreatitis Study Group. [PDF]
Necrotising pancreatitis, and particularly infected necrosis, are still associated with high morbidity and mortality. Since 2011, a step-up approach with lower morbidity rates compared to initial open necrosectomy has been established. However, mortality
Sebastian Rasch +27 more
doaj +2 more sources
Infected necrotizing pancreatitis: clinical features, microbial patterns, and outcomes in a Saudi tertiary center [PDF]
Infected necrotizing pancreatitis (INP) is a severe complication of acute pancreatitis (AP) associated with high morbidity and mortality, yet regional data remain limited.
Moaz Abulfaraj
doaj +2 more sources
A Rare but Life-Threatening Complication of Direct Endoscopic Necrosectomy: Tension Pneumoperitoneum With Pneumothorax and Hypercapnia due to Walled-Off Necrosis Rupture. [PDF]
Endoscopic ultrasonography (EUS)–guided drainage followed by direct endoscopic necrosectomy (DEN) is widely used as a minimally invasive treatment for walled‐off necrosis (WON). While this approach is considered effective and safe, serious complications may occur.
Otsuka Y +7 more
europepmc +2 more sources
Spider-Man in WONderland: Bending Biopsy Forceps to Facilitate Endoscopic Necrosectomy. [PDF]
Digestive Endoscopy, Volume 38, Issue 2, February 2026.
Hamada T, Saito T, Fujishiro M.
europepmc +2 more sources
AEG-AESPANC-OPGE-SIED-SPG Ibero-Latin American Guidelines on Acute Pancreatitis (iLATAM-AP). [PDF]
ABSTRACT Introduction Acute pancreatitis (AP) is a major cause of gastrointestinal hospitalizations worldwide. Although typically self‐limiting, up to one‐third of cases develop complications associated with increased morbidity and mortality. Despite recent advances that have improved outcomes, clinical heterogeneity necessitates updated, evidence ...
Cárdenas-Jaén K +44 more
europepmc +2 more sources
Immediate Endoscopic Necrosectomy for Walled-Off Pancreatic Necrosis: A First-Choice Option? [PDF]
Digestive Endoscopy, Volume 38, Issue 1, January 2026.
Hamada T +3 more
europepmc +2 more sources
Background/Aims Acute pancreatitis is a common condition of the digestive system, but sometimes it develops into severe cases. In about 10–20% of patients, necrosis of the pancreas or its periphery occurs.
Penghao Tang +7 more
doaj +1 more source
Endoscopic Step-up Approach for Walled-off Necrosis After Acute Pancreatitis. [PDF]
ABSTRACT This review outlines current interventional strategies for treating symptomatic walled‐off necrosis (WON) after necrotizing pancreatitis. Mortality from acute pancreatitis has improved, but late mortality, particularly from infected necrosis, remains a challenge. WON requires invasive treatment in cases of infection or symptoms.
Mukai S +13 more
europepmc +2 more sources
Extended Open Transgastric Necrosectomy (EOTN) as a Safer Procedure for Necrotizing Pancreatitis [PDF]
The treatment of infected necrotizing pancreatitis has evolved from time to time and the success of surgical intervention depends on the timing of necrosectomy. Bacterial infection occurs in 40–70% of patients with necrotizing pancreatitis. Infection is
Prasad Sasnur +4 more
doaj +1 more source

