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Endoscopic necrosectomy was introduced as a safe and effective treatment modality for infected pancreatic necrosis. Although there have been many reports of endoscopic drainage of retroperitoneal pancreatic necrosis, the optimal endoscopic management of ...
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Is endoscopic necrosectomy the way to go?
Pancreatic necrosis with the formation of walled-off collections is a known complication of severe acute pancreatitis. Infected necrotic pancreatic collections are associated with a high mortality rate.
James Weiquan Li, Tiing Leong Ang
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Hydrogen Peroxide Flushes for Necrotizing Pancreatitis in a High-Risk Surgical Patient: A Pathway for Durable Response Without Additional Endoscopic Intervention [PDF]
Necrotizing pancreatitis (NP) is characterized by severe pancreatic inflammation with necrosis and a systemic inflammatory response. We describe the case of a 32-year-old female with NP successfully treated with a modified protocol using hydrogen ...
Smriti Kochhar +2 more
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Endoscopic Versus Surgical Management for Infected Necrotizing Pancreatitis and Walled-Off Necrosis: A Systematic Review of Randomized Controlled Trials [PDF]
Background and Objectives: Infected necrotizing pancreatitis and walled-off necrosis are associated with substantial morbidity and mortality. The evolution from open necrosectomy to minimally invasive and endoscopic strategies has improved outcomes, yet ...
Manuela Mastronardi +8 more
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Infected necrotizing pancreatitis: clinical features, microbial patterns, and outcomes in a Saudi tertiary center [PDF]
Infected necrotizing pancreatitis (INP) is a severe complication of acute pancreatitis (AP) associated with high morbidity and mortality, yet regional data remain limited.
Moaz Abulfaraj
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Background/Aims: The endoscopic step-up approach is accepted as the preferred treatment for complicated or symptomatic walled-off necrosis (WON). Direct endoscopic necrosectomy (DEN) is an effective therapeutic option, but few reports describe long-term ...
Yeon Suk Kim +7 more
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Objectives Interventions for necrotizing pancreatitis are generally postponed until 4 weeks after the onset of acute pancreatitis, but there remains controversy about whether we should always wait >4 weeks or can intervene early when necessary. This meta‐
Yousuke Nakai +13 more
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Risk Factors for Bleeding during Endoscopic Necrosectomy: Are We Wiser Now?
Endoscopic necrosectomy (EN) in acute necrotizing pancreatitis has mortality benefits and may avert the requirement for surgery. However, bleeding is a common adverse event during EN.
Anurag Sachan, Surinder S. Rana
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Background: The conventional open necrosectomy was associated with high mortality and morbidities like secondary organ failure, incisional hernia, enterocutaneous fistula, and external pancreatic fistula.
Mohanasundaram Avudiappan +5 more
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Infected Necrosis in Severe Pancreatitis - Combined Nonsurgical Multi-Drainage with Directed Transabdominal High-Volume Lavage in Critically Ill Patients [PDF]
Background: Infection of pancreatic necrosis is a life-threatening complication during the course of acute pancreatitis. In critically ill patients, surgical or extended endoscopic interventions are associated with high morbidity and mortality. Minimally
Huber, W. +10 more
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