Results 21 to 30 of about 1,549,386 (358)
New England Journal of Medicine, 2000 BACKGROUND Neutralization of tumor necrosis factor a (TNF-alpha) for three to six months reduces the symptoms and signs of rheumatoid arthritis. However, the capacity of this approach to effect a more sustained benefit and its effect on joint damage are ...
eter +28 more
semanticscholar +1 more source
Frontiers in Surgery, 2019 Gastric necrosis with perforation is a rare and potentially life-threatening condition in childhood beyond the neonatal period. We report a case of gastric necrosis and perforation of a portion of the great curvature due to a massive gastric dilatation ...
Zlatan Zvizdic +3 more
doaj +1 more source
Advances in RIPK1 kinase inhibitors
Frontiers in Pharmacology, 2022 Programmed necrosis is a new modulated cell death mode with necrotizing morphological characteristics. Receptor interacting protein 1 (RIPK1) is a critical mediator of the programmed necrosis pathway that is involved in stroke, myocardial infarction ...
Lu Chen +13 more
doaj +1 more source
Signalisation apototique induite par les LDL oxydées Implication dans l’athérosclérose
Oléagineux, Corps gras, Lipides, 2006 The balance between vascular cell proliferation vs apoptosis plays a key role in vessel wall remodeling. Intimal migration and proliferation of smooth muscle cells (SMC), and secretion of extracellular matrix are involved in fibrous cap formation and ...
Negre-Salvayre Anne +2 more
doaj +1 more source
Paracetamol-induced fixed drug eruption presenting as eyelid skin necrosis
Indian Journal of Ophthalmology, 2018 Fixed drug eruption (FDE) is a type of drug-induced cutaneous disorder that characteristically presents with recurrence of similar lesion at the same skin or mucosal site as a result of systemic exposure to a drug.
Prajakta Kimmatkaar +3 more
doaj +1 more source
Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells [PDF]
Open Biology, 2016 Amyloidogenic protein aggregation impairs cell function and is a hallmark of many chronic degenerative disorders. Protein aggregation is also a major event during acute injury; however, unlike amyloidogenesis, the process of injury-induced protein ...
Andre L. Samson +7 more
doaj +1 more source
Acute and subchronic effects of petroleum on the freshwater fish Hoplias aff. malabaricus
Brazilian Journal of Biology, 2022 Petroleum water soluble fraction (WSF) impairs organisms, but damages may vary among cell and tissue levels. The aim of the present study was to evaluate the acute (24 h, 48 h, 72 h) and subchronic effects (36 days) of WSF (0%, 25% and 100%) in juveniles
R. M. Santos +6 more
doaj +1 more source
Apoptosis and Necrosis are Involved in the Toxicity of Sauropus androgynus in an In Vitro Study
Journal of the Formosan Medical Association, 2007 The raw juice of the young sticks and leaves of Sauropus androgynus (SA) has been widely used as a natural food for body weight reduction and vision protection in Taiwan and Southeast Asia.
Shih-Fing Yu +2 more
doaj +1 more source