The mycotoxin deoxynivalenol predisposes for the development of Clostridium perfringens-induced necrotic enteritis in broiler chickens [PDF]
Both mycotoxin contamination of feed and Clostridium perfringens-induced necrotic enteritis have an increasing global economic impact on poultry production. Especially the Fusarium mycotoxin deoxynivalenol (DON) is a common feed contaminant.
Antonissen, Gunther +13 more
core +15 more sources
Identification of a key residue for Oligomerisation and pore-formation of Clostridium perfringens NetB [PDF]
Necrotic enteritis toxin B (NetB) is a β-pore-forming toxin produced by Clostridium perfringens and has been identified as a key virulence factor in the pathogenesis of avian necrotic enteritis, a disease causing significant economic damage to the ...
Basak, Ajit K. +6 more
core +4 more sources
Elevated faecal ovotransferrin concentrations are indicative for intestinal barrier failure in broiler chickens [PDF]
Intestinal health is critically important for the welfare and performance of poultry. Enteric diseases that cause gut barrier failure result in high economic losses.
Callens, Chana +11 more
core +5 more sources
Zinc Glycinate Alleviates Necrotic Enteritis Infection in Broiler Chickens. [PDF]
This study evaluated zinc glycinate (ZG) on necrotic enteritis (NE) in chickens through two in vivo experiments and one in vitro experiment. In vivo, ZG was supplemented (study 1: 40–120 mg/kg; study 2: 100–160 mg/kg). In total, 192 (exp. 1) and 240 Cobb
Ng TT, Sparling BA, Selvaraj RK.
europepmc +2 more sources
Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins. [PDF]
Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic, neurologic and intestinal infections in humans and animals. The major toxins involved in diseases are alpha (CPA), beta (CPB), epsilon (ETX), iota (ITX), enterotoxin (
McClane, Bruce A +2 more
core +5 more sources
Prevalence, molecular detection, and histopathological analysis of necrotic enteritis in chickens. [PDF]
Background: With the significant growth of the global broiler industry, Clostridium perfringens-induced necrotic enteritis (NE) has become an ongoing challenge, causing considerable economic losses, particularly following the ban on antimicrobial growth
Kouchey AB +10 more
europepmc +2 more sources
NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens
The Clostridium perfringens necrotic enteritis B-like toxin (NetB) is a recently discovered member of the β-barrel pore-forming toxin family and is produced by a subset of avian C. perfringens type A strains.
Robert J Moore, Julian Ian Rood
exaly +3 more sources
Microbial shifts associated with necrotic enteritis [PDF]
An outbreak of necrotic enteritis (NE) is a complex process requiring one or a number of predisposing factors rather than just the presence of pathogenic Clostridium perfringens. Examples are dietary influences, such as high levels of non-starch polysaccharides and fishmeal, and factors that evoke epithelial cell damage, such as Fusarium mycotoxins in ...
Gunther Antonissen +2 more
exaly +3 more sources
Oral and parenteral vaccination of broiler chickens with Recombinant NetB antigen from Clostridium perfringens confers significant protection against necrotic enteritis. [PDF]
Background Necrotic enteritis is a devastating economic disease caused by Clostridium perfringens in poultry. NetB toxin from C. perfringens type G is the major responsible cause of necrotic enteritis.
Shamshirgaran MA, Golchin M.
europepmc +2 more sources
Variable protection after vaccination of broiler chickens against necrotic enteritis using supernatants of different Clostridium perfringens strains [PDF]
Freddy Haesebrouck +2 more
exaly +3 more sources

