Results 91 to 100 of about 345,328 (274)

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

A Case of Complete Rectal Prolapse in an In-Gilt

Case Reports in Veterinary Medicine, 2014
A seven-month-old in-gilt was presented with an intractable rectal prolapse. The prolapsed rectum was swollen, necrotic, and ulcerated. The pig was apparently healthy and had been ingesting high fibre feed materials, with little water.
Njoku Uchechukwu Njoku, Kelechi Theresa Jeremiah, Rock Odimma Ukaha, Chioma Frances Orajaka   +3 more
doaj   +1 more source

Unusual Necrotizing Uterine Adenocarcinoma in a Dog

Journal of Animal Reproduction and Biotechnology, 2017
A 2-year-old female Maltese dog was admitted with a history of pyometra and resulting peritonitis and septicemia. Uterine specimen sampled by ovariohysterectomy was processed routinely for histopathological observation.
Tae-Jung Kim, Sung-Shik Shin, Sang-Ik Park   +2 more
doaj   +1 more source

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]

, 2017
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl, Ballabio, Andrea, Bhattacharya, Somashubhra, Crowley, Jan R, Dehestani, Babak, Diwan, Abhinav, Epelman, Slava, Evans, Trent D, Fan, Daping, Holloway, Karyn B, Javaheri, Ali, Micevych, Paul S, Razani, Babak, Schilling, Joel D, Sergin, Ismail, Song, Eric, Stokes, Carl J, Weihl, Conrad C, Zayed, Mohamed A, Zhang, Xiangyu   +19 more
core   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Strangulated femoral hernia leading to lower extremity necrotizing soft tissue infection

Revista de la Facultad de Ciencias Médicas de Córdoba
This article presents a rare case of a necrotizing soft tissue infection secondary to a strangulated and perforated femoral hernia. The patient had presented several days after the onset of symptoms and was in septic shock due to spillage of intestinal ...
Ellie Zhang, Hayes Fountain, Timothy Trestrail, Joshua Kronenfeld, Carolina Jimenez, Robert Cubas   +5 more
doaj   +1 more source

Reasons for different therapeutic effects of high-intensity focused ultrasound ablation on excised uterine fibroids with different signal intensities on T2-weighted MRI: a study of histopathological characteristics

International Journal of Hyperthermia, 2019
Objective: The objective of this study was to explore the correlations between the therapeutic effect of high intensity focused ultrasound (HIFU) and histopathological characteristics of excised uterine fibroids with different signal intensities as ...
Haoran Huang, Jianbo Ran, Zhibo Xiao, Liping Ou, Xing Li, Jie Xu, Qi Wang, Zhibiao Wang, Faqi Li   +8 more
doaj   +1 more source

Design of a Debridement Device Using Impinging Jets [PDF]

, 2016
Chronic wound care is a significant burden on the healthcare system, affecting an estimated three to six million Americans, manifesting as ulcers associated with restricted blood flow, diabetes mellitus, or pressure. Treatment is frequently unsuccessful,
Hogan, Nora Catherine, Hunter, Ian, Raynal, Ashley B.   +2 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source