Results 101 to 110 of about 162,318 (308)

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

iMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang, Shuzi Liu, Laurence Don Wai Luu, Yongzhi Zhai, Chenliang Zhu, Zhaomin Feng, Yao Tan, Linglong Wan, Jie Wang, Juan Zhou, Jing Wang, Lixin Xie, Quanyi Wang, Fei Xie   +13 more
wiley   +1 more source

Co‐Existing Non‐Occlusive Splenic Vein and Superior Mesenteric Vein Thrombosis in an Acute Necrotic Pancreatitis Patient—A Case Report

Clinical Case Reports
Case report of a case of acute pancreatitis (AP) at a patient previously known with essential thrombocytosis (ET). The most redoubtable complications of AP in this case were: pancreatic necrosis and splahnic vein thrombosis (SVT). Patient was followed‐up
Andreea Irina Ghiță, Arina Ilinca Gheorghe, Georgiana Elena Beteringhe, Andreea Ramona Treteanu, Mihai Radu Pahomeanu   +4 more
doaj   +1 more source

Necrotizing fungal infection due to Saksenaea erythrospora: A case report and review of literature

Indian Journal of Ophthalmology, 2018
Mucormycosis caused by Saksenaea erythrospora is an emerging infection seen with soil contamination, burns and/or nosocomial infections. PCR amplification and internal transcribed spacer sequencing is gold standard for its identification. Here, we report
Bipasha Mukherjee, Debi Kundu
doaj   +1 more source

A recipe for myositis : nuclear factor κB and nuclear factor of activated T-cells transcription factor pathways spiced up by cytokines [PDF]

, 2017
Nuclear factor κB (NF-κB) is a well-known pro-inflammatory transcription factor that regulates the expression of the tissue’s immune-active components, which include cytokines, chemokines and adhesion molecules.
De Paepe, Boel
core   +3 more sources

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Exhaustion of the immune system by Group A Streptococcus necrotizing fasciitis: the occurrence of late secondary infections in a retrospective study

Trauma Surgery & Acute Care Open, 2019
Background Necrotizing fasciitis is a potentially lethal condition for which early and adequate treatment with surgical debridement and broad-spectrum intravenous antibiotics are essential for survival. It is hypothesized that Group A Streptococcus (GAS)
Luke P H Leenen, Falco Hietbrink, Femke Nawijn, Emma C E Wassenaar, Diederik P J Smeeing, Bart J M Vlaminckx, Jan Siert K Reinders, Jan Wille   +7 more
doaj   +1 more source

Acquired heart block: A possible complication of patent ductus arteriosus in a preterm infant [PDF]

, 2008
A large patent ductus arteriosus (PDA) is a frequently encountered clinical problem in extremely low birth weight (ELBW) infants. It leads to an increased pulmonary blood flow and in a decreased or reversed diastolic flow in the systemic circulation ...
Andreas Holzinger, Baylen B, Bucci G, Christoph Döhlemann, Evans N, Georg Münch, Griffin JH, Hans-Georg Dietz, Holger Till, Limperopoulos C, Mendicini M, Monika Grasser, Rashmi Mittal, Skelton R, Walther FJ   +14 more
core   +1 more source

Pregnancy Outcomes and Postnatal Health From Transferred Mosaic Embryos Following Preimplantation Genetic Testing for Aneuploidy

iNew Medicine, EarlyView.
This illustration synthesizes the methods and conclusion of this study, demonstrating that the transfer of mosaic embryos following reimplantation genetic testing for aneuploidy does not increase the risk to postnatal health. ABSTRACT Next‐generation sequencing (NGS) has increased the detection of mosaic embryos during preimplantation genetic testing ...
Lili Chen, Dehuan Huang, Jingcheng Sang, Yiqi Yin, Caiyun Wu, Yan Hao, Dawei Chen, Zhiguo Zhang, Yunxia Cao, Ri‐Cheng Chian, Ping Zhou   +10 more
wiley   +1 more source

Utility of GutCheck-NEC and e-NEC Scoring Systems in Assessing the Risk of Necrotizing Enterocolitis in Preterm Infants

Güncel Pediatri
Introduction: Necrotizing enterocolitis (NEC) is one of the leading gastrointestinal emergencies causing significant morbidity and mortality in premature neonates. This study aimed to evaluate the effectiveness of the GutCheck-NEC (GCN) and e-NEC scoring
Berna Egehan Örüncü, Nuriye Ebru Ergenekon, İbrahim Murat Hirfanoğlu, Canan Türkyılmaz, Eray Esra Önal, Esin Koç   +5 more
doaj   +1 more source

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source