Results 31 to 40 of about 128,451 (316)

Gut bacteria and necrotizing enterocolitis: cause or effect? [PDF]

, 2015
Development of necrotising enterocolitis (NEC) is considered to be dependent on the bacterial colonisation of the gut. With little concordance between published data and a recent study failing to detect a common strain in infants with NEC, more questions
Stewart, Christopher, Cummings, Stephen
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

A Rare Coexistence: Gangrenous Cystitis and Necrotizing Fasciitis [PDF]

Gangrenous cystitis is an exceedingly uncommon diagnosis characterized by bladder mucosa and submucosal necrosis. The presence of non-specific symptoms and signs complicates the diagnostic process.
Erim Erdem, Gizem Aydın, Melih Bıyıkoğlu, Yasemin Yuyucu Karabulut   +3 more
core   +1 more source

Necrotizing sialometaplasia of the tonsillar pillar. An unusual case [PDF]

, 2021
Necrotizing Sialometaplasia (NS) is a rare, benign, self-limited, inflammatory and necrotizing reaction of the salivary glandular tissue. Due to the clinical picture (a painful ulcer with well-defined edges), and histopathological characteristics ...
Gaitán Cepeda, Luis Alberto, Santos-Jaimes, Edmundo, Hernández-Flores, Julissa-Brillit, L. Gaitán-Cepeda, J. Hernández-Flores, E. Santos-Jaimes   +5 more
core   +1 more source

ClpX-dependent regulatory pathway exacerbates Streptococcus pyogenes pathogenesis in diabetic skin infection

mBio
Diabetes is associated with impaired immune function and increased susceptibility to severe bacterial infections, yet the pathogen-encoded mechanisms that exacerbate disease in this context remain poorly defined.
Shuiqiao Liu, Anne L. Rosen, Benjamin S. Olson, Yongke Lu, Suzanne Hickerson, Andrew L. Kau, Scott J. Hultgren, Michael G. Caparon, Wei Xu   +8 more
doaj   +1 more source

Interleukin‐1α Mediates Pancreatic Fibroblast Activation, Regulates Immune Cell Recruitment and Fibrosis in Acute and Chronic Pancreatitis

Advanced Science, EarlyView.
During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum, Shenja Buchholz, Hanna Schifter, Sabine Ameling, Leif Steil, Ben Lewin Becker, Elke Hammer, Georg Homuth, Uwe Völker, Barbara M. Bröker, Lukas Zierke, Frank Ulrich Weiss, Juliane Glaubitz, Matthias Sendler   +13 more
wiley   +1 more source

Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis

Clinical Case Reports
Acute necrotizing otitis media is a severe middle ear infection which causes necrosis of the tympanic cavity. A 54‐year‐old female was presented who suffered from diabetes mellitus and end‐stage renal disease presenting with severe otalgia, initially ...
Ermia Mousavi Mohammadi, Mohsen Rajati, Hossein Zarrinfar   +2 more
doaj   +1 more source

Leighs disease: powerhouse failure

MRIMS Journal of Health Sciences, 2018
Leigh disease, also known as juvenile sub acute necrotizing encephalomyelopathy, Leigh syndrome, infantile sub acute necrotizing encephalomyelopathy, and sub acute necrotizing encephalomyelopathy (SNEM), is a rare inherited neurometabolic disorder that ...
Himanshu Dua, Radhika Mantry
doaj   +1 more source

Massive necrotizing fasciitis following bellow-knee arterial surgery: A therapeutic challenge [PDF]

Vojnosanitetski Pregled, 2015
Introduction. Necrotizing fasciitis is a rare, progressive bacterial infection of superficial fascia followed by secondary subcutaneous tissue necrosis.
Popov Petar, Tanasković Slobodan, Sotirović Vuk, Nenezić Dragoslav, Radak Đorđe   +4 more
doaj   +1 more source

Penile Necrotizing Fasciitis (Fournier's Gangrene) after Penile Prosthesis Implant in diabetic patient treated conservatively – A case report. [PDF]

International Journal of Medical Arts, 2020
Background: Penile abscess and necrotizing fasciitis are very rare. Diabetes mellitus is the common risk factors. In our practice, this is the first reported case of penile necrotizing fasciitis after penile prosthesis insertion.
Nabeel Kuwaijo, Mohammed Abo Elmagd, Ponnusamy Mohan   +2 more
doaj   +1 more source