Results 151 to 160 of about 57,553 (263)
In infants with necrotising enterocolitis (NEC), excessive inflammation and epithelial cell death promote the epithelial–mesenchymal transition (EMT), leading to damage to intestinal barriers and the translocation of bacteria and toxins. In addition, inflamed epithelia release cytokines to strengthen the inflammatory response.
Xiao‐Chen Liu +12 more
wiley +1 more source
Piezo1 functions as a context‐dependent mechanotransduction node linking mechanical cues to inflammation, tissue remodelling and metabolic regulation in digestive homeostasis and disease. In epithelial, immune, stromal and endocrine cells, Piezo1‐mediated Ca2+ signalling contributes to barrier and mucus homeostasis, epithelial renewal and repair ...
Yuan Xia +6 more
wiley +1 more source
Gut Microbiota Dysbiosis Mediates 125I‐Induced Radiation Colitis via Host Transcriptional Regulation
ABSTRACT Background Iodine‐125 (125I) seed therapy is recognized for treating abdominal solid tumors with minimal adjacent tissue damage but may induce radiation colitis when its implantation near colonic tissues, leading to a poor prognosis. Nevertheless, the underlying pathogenesis is not well understood.
Pingping Liu +8 more
wiley +1 more source
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou +29 more
wiley +1 more source
Cognitive assessment in children with intestinal failure on and weaned off parenteral nutrition
Abstract Objectives Children with intestinal failure (IF) are vulnerable to adverse cognitive outcomes. We assessed intelligence quotient (IQ) and identified associated factors. Methods Multicentre international cross‐sectional study in children with IF and weaned children, treated at Erasmus MC Sophia Children's Hospital, Amsterdam UMC Emma Children's
Rozemarijn A. L. Duister +14 more
wiley +1 more source
Abstract Introduction Fetal growth restriction (FGR) is associated with an increased risk of neonatal morbidity and mortality. Current diagnostic criteria for FGR do not discriminate between constitutionally small and pathologically restricted fetuses.
Mohammad A. Salameh +6 more
wiley +1 more source
Katherine B Snyder,1,2 Chase L Calkins,3 Alena Golubkova,1,2 Tyler Leiva,1,2 Camille Schlegel,1 Catherine J Hunter1,2 1Division of Pediatric Surgery, Oklahoma City, OK, 73104, USA; 2Department of Surgery, The University of Oklahoma Health Sciences Center,
Schlegel C +5 more
core
Methods of Assessing Postoperative Pain in Infants (0–12 Months): A Scoping Review
ABSTRACT Infants undergoing surgery experience postoperative pain beyond acute short‐lasting procedural pain and have variable analgesic needs. Assessing pain in this nonverbal population presents challenges for clinicians and parents. Given the short‐ and long‐term effects of pain and its treatment, timely and accurate assessment of pain is vital. The
Jeewan Jyoti +5 more
wiley +1 more source
ABSTRACT Objective To evaluate whether fetuses exposed to threatened preterm labor (PTL) without intra‐amniotic infection or inflammation (IAI), who were born ≥ 34 weeks' gestation, show signs of cardiac remodeling and dysfunction at admission and 4 weeks after the episode of threatened PTL.
C. Murillo +11 more
wiley +1 more source

