Results 71 to 80 of about 84,162 (262)

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer, Arie Arensman, H. Rob Taal, Emilie P. Buddingh, Su Ming Sun, Anthon Hulsmann, Lenneke Waals‐Prinzen   +6 more
wiley   +1 more source

Necrotizing Fasciitis of the Lower Limb – A Prospective Study of Prognostic Factors Affecting Mortality [PDF]

Malaysian Orthopaedic Journal, 2009
Necrotizing fasciitis is a life and limb threatening soft tissue infection with a high mortality rate. This study tries to identify the possible risk factors that contribute to mortality in patients with necrotizing fasciitis involving a lower limb.
EK Chee, MK Kwan, EH Khoo
doaj  

Necrotizing fasciitis

Journal of British Surgery, 1991
Abstract Ten cases of necrotizing fasciitis are reviewed. Three patients died but only two of these deaths were due to uncontrolled septicaemia. All isolated organisms were sensitive to a combination of piperacillin and ampicillin which we now regard as the initial antibiotic combination of choice.
S K, Asfar, A, Baraka, T, Juma, A, Ma'Rafie, T, Aladeen, H, al Sayer   +5 more
openaire   +2 more sources

Successful Treatment of Spesolimab in a Haemodialysis Patient With Acutely Flaring Generalised Pustular Psoriasis

JEADV Clinical Practice, Volume 4, Issue 5, Page 1190-1192, December 2025.
Capsule Summary Generalised pustular psoriasis is one of the severe dermatological disorders. The use of biologics in psoriatic patients with end‐stage renal disease is rare, and the safety information on biologics treatment in such patients is limited.
Yasuyuki Fujita, Sota Itamoto, Akihiro Orita, Kunihiro Kawashima, Satoko Shimizu   +4 more
wiley   +1 more source

Case report: A rare case of simultaneous necrotizing fasciitis of the breast and forearm

Frontiers in Medicine
Necrotizing fasciitis is an aggressive bacterial infection that causes necrosis of the fascia and subcutaneous tissues with rapid progression and high mortality.
Ruofei Xu, Tingting Fang, Weikang Cai
doaj   +1 more source

Necrotizing Fasciitis Caused by Hypermucoviscous Klebsiella pneumoniae in a Filipino Female in North America

Western Journal of Emergency Medicine, 2014
Necrotizing fasciitis caused by Klebsiella pneumoniae has been described in Southeast Asia, but has only recently begun to emerge in North America. The hypermucoviscous strain of K.
Ng, Daniel, Frazee, Brad
doaj   +1 more source

Clindamycin and daptomycin failure in PVL‐positive MRSA infection of the skin and soft tissue

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Michael Zolotas, Kamran Ghoreschi, Ulrike Blume‐Peytavi, Rasmus Leistner, Daniel Humme   +4 more
wiley   +1 more source

Exploration of Human Skin Phageome to Reveal Endolysins and Novel Antimicrobial Peptides for Therapeutic Applications

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study uncovers diverse endolysins and novel antimicrobial peptides from the human skin phageome, highlighting their potential to target antibiotic‐resistant pathogens and disrupt virulence mechanisms, paving the way for next‐generation skin therapeutics.
Jibon Kumar Paul, Arzuba Akter, Nurnabi Azad Jewel, Mohimenul Haque Rolin, Daniyal Karim, Raphael Kabir Niloy, Shakhinur Islam Mondal   +6 more
wiley   +1 more source

Heuristics, biases, and cognitive pitfalls of emergency teledermatology: Navigating the fine line between making and avoiding diagnostic errors

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Charbel Skayem, Tu‐Anh Duong
wiley   +1 more source

Large‐Bore Vacuum Suction Biopsy of Pediatric Soft Tissue Tumors: A 5‐Year Retrospective Analysis of Safety and Effectiveness

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Introduction Percutaneous large‐bore vacuum suction biopsy (LBVSB) is an innovative alternative to open surgical biopsy and minimally invasive image‐guided percutaneous core needle biopsy (PCNB) for pediatric soft tissue tumors. This study reviews our experience using this modality.
Abhinav R. Balu, Shankar Rajeswaran, Nitin R. Wadhwani, Ian Gelarden, Elizabeth Sokol, Joseph R. Ness, Darshan E. Variyam, Timothy Lautz, Joe B. Baker   +8 more
wiley   +1 more source