Pathophysiology of acute experimental pancreatitis: Lessons from genetically engineered animal models and new molecular approaches [PDF]
The incidence of acute pancreatitis is growing and worldwide population-based studies report a doubling or tripling since the 1970s. 25% of acute pancreatitis are severe and associated with histological changes of necrotizing pancreatitis. There is still
Anne Barbara Tietz +38 more
core +1 more source
Previous research focused on the qualitative discussion of the correlation between surgical time and mortality in acute pancreatitis (AP). Recommendations for surgical timing of necrotizing pancreatitis are delayed as far as possible, without ...
Jiawei Luo +7 more
doaj +1 more source
Significance of thromboxane A2 and prostaglandin I2 in acute necrotizing pancreatitis in rats [PDF]
Plasma thromboxane concentrations were found to be significantly elevated in acute necrotizing pancreatitis in rats, whereas prostaglandin I2 levels were not. The significance of these alterations was investigated. Pancreatitis was induced by injecting 5%
Kort, W.J. (Wil) +3 more
core +1 more source
Necrotizing forms of acute pancreatitis, as the most severe in terms of prognosis, occur in 25–30% of cases with a mortality rate of 27–32%, while in most cases these are adults of working age, which emphasizes the social significance of this problem ...
A. Ch. Askerov +5 more
doaj +1 more source
Randomized controlled trials of antibiotic prophylaxis in severe acute pancreatitis:Relationship between methodological quality and outcome [PDF]
AIM: To evaluate the methodological quality of randomized controlled trials (RCTs) of systemic antibiotic prophylaxis in severe acute pancreatitis in relation to outcome.
Besselink, Marc G. H. +6 more
core +2 more sources
Background Infected necrosis complicates 10% of all acute pancreatitis episodes and is associated with 15–20% mortality. The current standard treatment for infected necrotizing pancreatitis is the step-up approach (catheter drainage, followed, if ...
Janneke van Grinsven +35 more
doaj +1 more source
Панкреатогенные инфекции: значение микробиологического мониторинга и степени проникновения антимикробных химиотерапевтических средств в поджелудочную железу при определении тактики их лечения [PDF]
В обзоре представлены сведения о спектре микроорганизмов, инициирующих развитие клинико-морфологических форм панкреатогенных инфекций. Особое внимание в обзоре уделено выбору при остром панкреатите антибактериальных препаратов, основанному на показателях
Афанасьев, Ю. И. +3 more
core +1 more source
Pro/con debate: antifungal prophylaxis is important to prevent fungal infection in patients with acute necrotizing pancreatitis receiving broad-spectrum antibiotics [PDF]
When critically ill patients with pancreatitis develop infection of the pancreas, the ongoing management of such patients becomes difficult. Sufficient evidence supports the use of broad-spectrum antibiotic prophylaxis to prevent the development of ...
Eggimann, P. +2 more
core +2 more sources
Background The initial treatment of acute necrotizing pancreatitis is conservative. Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis.
Houdijk Lex PJ +30 more
doaj +1 more source
LOCAL-FOCAL NECROTIZING HAEMORRHAGIC ACUTE PANCREATITIS: A CASE REPORT AND REVIEW OF LITERATURE [PDF]
A rare case of a twenty-six years old male, presented to emergency department of Mosul General Hospital in Mosul, as acute abdomen, on exploration, acute local- focal necrotizing pancreatitis was found, presented as a tumour like swelling related to the ...
Mahmood A.H. Salih
doaj +1 more source

