Results 281 to 290 of about 323,794 (349)

MUTE‐Seq: An Ultrasensitive Method for Detecting Low‐Frequency Mutations in cfDNA With Engineered Advanced‐Fidelity FnCas9

open access: yesAdvanced Materials, EarlyView.
An advanced‐fidelity CRISPR nuclease, FnCas9‐AF2, is rationally engineered to discriminate single‐base mismatches with unprecedented level precision. Integrated into the MUTE‐Seq workflow, FnCas9‐AF2 depletes wild‐type cell‐free DNA, thereby exposing rare tumor‐derived mutant DNA (a molecular “needle in a haystack”).
Sunghyeok Ye   +20 more
wiley   +1 more source

Micro‐Strain Responsive Near‐Infrared Mechanoluminescence for Potential Nondestructive Artificial Joint Stress Imaging

open access: yesAdvanced Materials, EarlyView.
In situ and real‐time stress sensing during total knee replacement procedure is expected to be realized based on near‐infrared mechanoluminescent phosphor of Sr3Sn1.98Sb0.02O6.99, which has the lowest strain sensitivity as low as 50 µst. Abstract Recently, joint replacement surgery is facing significant challenges of patient dissatisfaction and the ...
Wenhao Li   +9 more
wiley   +1 more source

Enlarged cavum septum pellucidum as a neuroimaging signature of head impact exposure. [PDF]

open access: yesBrain Commun
Kamps S   +11 more
europepmc   +1 more source

Recent Advances in Reactive Microdroplets for Clean Water and Energy

open access: yesAdvanced Materials, EarlyView.
Reactive microdroplets enable precise and sustainable chemistry at small scales. This review explores their role as confined reactors and dynamic interfaces for synthesizing functional materials, fuels, and microdevices. It offers a critical perspective on how droplet‐based platforms can drive next‐generation technologies in clean energy, environmental
Qiuyun Lu   +4 more
wiley   +1 more source

Responsive Polyelectrolyte Brushes in Applications: Functions, Stimuli, and Design Considerations

open access: yesAdvanced Materials, EarlyView.
With advances in the synthesis of polyelectrolyte brushes, these coatings of surface‐grafted chains find uses in an increasing number of applications. This review summarizes three core aspects of these brushes: how they introduce functionality to surfaces; how external stimuli influence their properties; and what practical considerations should be ...
Leon A. Smook   +3 more
wiley   +1 more source

Characterizing visual read tau-PET-negative participants with Alzheimer's disease dementia. [PDF]

open access: yesAlzheimers Dement
Rikken RM   +17 more
europepmc   +1 more source

Waste‐Free Closed‐Loop‐Recyclable and Thermally Superinsulating Polyimide Aerogels Utilizing Diels‐Alder Chemistry

open access: yesAdvanced Materials, EarlyView.
A synthetic protocol for thermally recyclable poly(amide‐imide) aerogels based on Diels–Alder chemistry is presented. Prepared from furan‐modified poly(amide‐imide) and bismaleimide, these aerogels offer thermal superinsulation and excellent thermo‐mechanical performance.
Yufei Xiong   +5 more
wiley   +1 more source

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