Results 61 to 70 of about 323,794 (349)
Finding your way into an open online learning community [PDF]
, 2008 Making educational materials freely available on the web is not only a noble enterprise, but also fits the call of helping people to become lifelong learners; a call which gets louder and louder every day.
John van der Baaren +3 more
core +2 more sources
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
, 2007 De uitslag van het referendum op 1 juni 2005 over het Europees Grondwettelijke Verdrag legde op dramatische wijze de kloof bloot tussen politieke en publieke opinie als het gaat over Europese beleidsvorming. Tegelijk heeft het Grondwettelijk Verdrag laten zien dat nationale politici en bestuurders er niet in slagen te functioneren als adequate ...
openaire +3 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Nederlandse export: bloemen en groenten [PDF]
, 1999 In welke economische activiteit is Nederland relatief sterk? Om dit te meten is het gebruikelijk om de export van Nederlandse producten of bedrijfstakken te vergelijken met de export van deze producten van andere landen.
Hinloopen, J. (Jeroen) +1 more
core
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Formulieren in Nederland [PDF]
Tijdschrift voor Taalbeheersing, 2008 Contains fulltext : 67972.pdf ( ) (Open Access)
Jansen, C.J.M., Lentz, L.
openaire +2 more sources
Entrepreneurship in the Netherlands: Ambitious entrepreneurs: the driving force for the next millennium [PDF]
Studie naar de dynamiek van jonge bedrijven en snelgroeiende bedrijven in Nederland, Denemarken, het Verenigd Koninkrijk, de Verenigde Staten en Zweden. In Nederland zijn er relatief weinig bedrijven met hoge werkgelegenheidsgroei.
Jacqueline Snijders, Sander Baljé
core
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source