Unmet Need for Mental Health Services Among High School Students Experiencing Persistent Feelings of Sadness or Hopelessness - Youth Risk Behavior Survey, United States, 2025. [PDF]
Kiplagat SJ +7 more
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
From streets to podium: addressing early pregnancies and health challenges
Debapriya Bhattacharyya
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Public Health Information Seeking Behaviours Among Young Adults With Migrant Backgrounds in Australia: A Cross-Sectional Study. [PDF]
Mahad M, Pourmarzi D.
europepmc +1 more source
“… The Need, the Need for Speed!” [PDF]
openaire +1 more source
On needing 'need': an exploration of the construction of the child with 'additional needs' [PDF]
My research takes a social work perspective to investigate the concept of the child with ‘additional needs’. This concept arose out of the Labour Government’s programme ‘Every Child Matters’ (HM Government, 2003) which proposed that children’s needs for support should be picked up at an earlier point by an integrated Children’s Services consisting of ...
openaire
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Unmet health and social service needs in LGBTQ+ older adults in California: a quantitative analysis of a large community-based sample. [PDF]
Vupputuri P +5 more
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source

