Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Enhancing decision quality through computer-based decision aids: how promotional interventions and Need for Cognition shape effectiveness in online consumer choices. [PDF]
Vogrincic-Haselbacher C +5 more
europepmc +1 more source
Explaining News Trust in Social Media News during the COVID-19 Pandemic-The Role of a Need for Cognition and News Engagement. [PDF]
Kožuh I, Čakš P.
europepmc +1 more source
Cognitive assessment in diabetes: the need for consensus [PDF]
M W, Strachan, B M, Frier, I J, Deary
openaire +2 more sources
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Becoming a "Hungry Mind": Stability and Change in Need for Cognition across Adolescence. [PDF]
Lavrijsen J +4 more
europepmc +1 more source
Partner influences on ICT use variety among middle-aged and older adults: The role of need for cognition. [PDF]
Chopik WJ, Francis J.
europepmc +1 more source
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
Need for Cognition Predicts Academic Interest Development but Not the Other Way Around: A Longitudinal Study of Secondary School Students. [PDF]
Matthes J, Scherrer V, Preckel F.
europepmc +1 more source
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source

