Results 121 to 130 of about 4,207,426 (309)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Beyond radicalization: the 3N model and its application to criminal attitudes in high-risk contexts

Frontiers in Psychology
IntroductionThis research integrates criminological and psychological literature by applying the 3N model of radicalization to predict criminal attitudes. Specifically, we conceptualize “need” as the search for meaning, “networks” as deviant associations,
Jocelyn J. Bélanger, Michael Wolfowicz, Hayat Mohammad, Roberto M. Lobato, Michelle Blaya Burgo, Laura Rico-Bustamante, José M. Martín-Criado, Manuel Moyano   +7 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

The Metaphysical Subject as Background to the Early Wittgenstein"s Epistemology [PDF]

, 2003
Proposition 4.1121 of the Tractatus states that epistemology is the philosophy of psychology. What should we take this to mean? Philosophy, on Tractarian terms, is an activity by which thoughts are clarified.
Armstrong, Brian
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The problem of labels in e-assessment of diagrams [PDF]

, 2008
In this short paper we explore a problematic aspect of automated assessment of diagrams. Diagrams have partial and sometimes inconsistent semantics.
Jayal, A, Shepperd, M J
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Formal and non-formal approaches to the notion of "Risk" : a historical perspective [PDF]

, 2008
The paper will focus on the early texts of Galileo Galilei (1613~1623) and Daniel Bernoulli (1738) as examples of pure combinatorical analysis and perspectively considerations within the mathematical discipline of probability theory.
Linhard, Frank
core